Pregnancy and herbal medicines: An unnecessary risk for women's healthA narrative review

被引:31
作者
Bruno, Luciana O. [1 ]
Simoes, Ricardo Santos [2 ]
Simoes, Manuel de Jesus [3 ]
Batista Castello Girao, Manoel Joao [1 ]
Grundmann, Oliver [4 ,5 ]
机构
[1] Fed Univ Sao Paulo UNIFESP, Dept Gynecol, BR-04021001 Sao Paulo, Brazil
[2] Univ Sao Paulo, Dept Obstet & Gynecol, BR-05508010 Sao Paulo, Brazil
[3] Fed Univ Sao Paulo UNIFESP, Dept Morphol & Genet, BR-04021001 Sao Paulo, Brazil
[4] Univ Florida UFL, Coll Pharm, Dept Med Chem, Gainesville, FL 32611 USA
[5] Univ Florida UFL, Coll Nursing, Dept Biobehav Nursing Sci, Gainesville, FL 32611 USA
关键词
herbal medicine; pregnancy risks; teratogenicity; toxicity; COHOSH CAULOPHYLLUM-THALICTROIDES; STANDARD RESEARCH COLLABORATION; ANTIFERTILITY ACTIVITY; ALTERNATIVE MEDICINE; BIOLOGICAL-ACTIVITIES; UTERINE TISSUE; OFFICINALIS L; UNITED-STATES; PLANTS; COMPLEMENTARY;
D O I
10.1002/ptr.6020
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The indiscriminate use of herbal medicines to prevent or to heal diseases or even the use for questionable purposes such as weight loss has received both interest and scrutiny from the scientific community and general public alike. An increasing number of women put their own and the unborn child's health at risk due to a lack of knowledge about the phytochemical properties and adequate use of herbal medicine (phytomedicines or herbal supplements) and lack of communication with their healthcare provider. The purpose of this narrative review was to summarize the use of herbal medicines during pregnancy and their potential toxic effects to highlight the importance of caution when prescribing herbal medicines or supplements for women, because, in addition to suffering interactions and a great amount of information obtained in preclinical predictive studies, assessment of nephrotoxicity, neurotoxicity, hepatotoxicity, genotoxicity, and teratogenicity of traditional medicinal herbs still remains scarce in the clinical setting.
引用
收藏
页码:796 / 810
页数:15
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