Pharmacokinetic Model-Driven Remifentanil Administration in the Morbidly Obese The 'Critical Weight' and the 'Fictitious Height', a Possible Solution to an Unsolved Problem?

被引:14
作者
La Colla, L. [1 ]
Albertin, A. [2 ]
La Colla, G. [3 ]
机构
[1] Univ Vita Salute San Raffaele, IRCCS H San Raffaele, Sch Med, Dept Anesthesiol, I-20132 Milan, Italy
[2] IRCCS Multimed, Dept Anesthesiol, Milan, Italy
[3] Univ Modena & Reggio Emilia, Dept Anaesthesiol, Modena, Italy
关键词
Obese Patient; Pharmacokinetic Parameter; Remifentanil; Lean Body Mass; Pharmacokinetic Model;
D O I
10.2165/00003088-200948060-00005
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:397 / 398
页数:2
相关论文
共 5 条
  • [1] Caution when lean body weight is used as a size descriptor for obese subjects
    Green, B
    Duffull, S
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2002, 72 (06) : 743 - 744
  • [2] James W P T, 1976, RES OB REP DHSS MRC
  • [3] Quantification of lean bodyweight
    Janmahasatian, S
    Duffull, SB
    Ash, S
    Ward, LC
    Byrne, NM
    Green, B
    [J]. CLINICAL PHARMACOKINETICS, 2005, 44 (10) : 1051 - 1065
  • [4] LACOLLA L, 2007, 1 WORLD C TOT INTR A
  • [5] Influence of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil .1. Model development
    Minto, CF
    Schnider, TW
    Egan, TD
    Youngs, E
    Lemmens, HJM
    Gambus, PL
    Billard, V
    Hoke, JF
    Moore, KHP
    Hermann, DJ
    Muir, KT
    Mandema, JW
    Shafer, SL
    [J]. ANESTHESIOLOGY, 1997, 86 (01) : 10 - 23