Clinical practice guidelines for the management of adult diffuse gliomas

被引：256

作者：

Jiang, Tao ^{[1
,2
,3
,4
,5
]}

Nam, Do-Hyun ^{[6
]}

Ram, Zvi ^{[7
]}

Poon, Wai-Sang ^{[8
]}

Wang, Jiguang ^{[9
]}

Boldbaatar, Damdindorj ^{[10
]}

Mao, Ying ^{[11
]}

Ma, Wenbin ^{[12
]}

Mao, Qing ^{[13
]}

You, Yongping ^{[14
]}

Jiang, Chuanlu ^{[15
]}

Yang, Xuejun ^{[16
]}

Kang, Chunsheng ^{[16
]}

Qiu, Xiaoguang ^{[17
]}

Li, Wenbin ^{[2
]}

Li, Shaowu ^{[1
]}

Chen, Ling ^{[18
]}

Li, Xuejun ^{[19
]}

Liu, Zhixiong ^{[19
]}

Wang, Weimin ^{[20
]}

Bai, Hongmin ^{[20
]}

Yao, Yu ^{[10
]}

Li, Shouwei ^{[21
]}

Wu, Anhua ^{[22
]}

Sai, Ke ^{[23
]}

Li, Guilin ^{[1
]}

Yao, Kun ^{[24
]}

Wei, Xinting ^{[25
]}

Liu, Xianzhi ^{[25
]}

Zhang, Zhiwen ^{[26
]}

Dai, Yiwu ^{[27
]}

Lv, Shengqing ^{[28
]}

Wang, Liang ^{[29
]}

Lin, Zhixiong ^{[21
]}

Dong, Jun ^{[30
]}

Xu, Guozheng ^{[31
]}

Ma, Xiaodong ^{[18
]}

Zhang, Wei ^{[2
,4
]}

Zhang, Chuanbao ^{[2
]}

Chen, Baoshi ^{[2
]}

You, Gan ^{[2
]}

Wang, Yongzhi ^{[2
]}

Wang, Yinyan ^{[2
]}

Bao, Zhaoshi ^{[2
]}

Yang, Pei ^{[2
]}

Fan, Xing ^{[1
]}

Liu, Xing ^{[1
]}

Zhao, Zheng ^{[1
]}

Wang, Zheng ^{[2
]}

Li, Yiming ^{[2
]}

机构：

[1] Capital Med Univ, Beijing Neurosurg Inst, 119 South 4th Ring Rd West, Beijing 100070, Peoples R China

[2] Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, Beijing 100070, Peoples R China

[3] Beijing Inst Brain Disorders, Ctr Brain Tumor, Beijing 100070, Peoples R China

[4] China Natl Clin Res Ctr Neurol Dis, Beijing 100070, Peoples R China

[5] Chinese Acad Med Sci, Res Units Accurate Diag & Treatment Brain Tumors, Beijing 100730, Peoples R China

[6] Samsung Med Ctr, Dept Neurosurg, Seoul, South Korea

[7] Tel Aviv Med Ctr & Sch Med, Dept Neurosurg, Tel Aviv, Israel

[8] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Neurosurg, Hong Kong, Peoples R China

[9] Hong Kong Univ Sci & Technol, Dept Chem & Biol Engn, Div Life Sci, Hong Kong, Peoples R China

[10] Mongolian Natl Univ Med Sci, Sch Biomed, Dept Physiol, Ulan Bator, Mongolia

[11] Fudan Univ, Huashan Hosp, Dept Neurosurg, Shanghai 200040, Peoples R China

[12] Chinese Acad Med Sci & Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Neurosurg, Beijing 100730, Peoples R China

[13] Sichuan Univ, West China Hosp, West China Med Sch, Dept Neurosurg, Chengdu 610041, Peoples R China

[14] Nanjing Med Univ, Dept Neurosurg, Affiliated Hosp 1, Nanjing 210029, Peoples R China

[15] Harbin Med Univ, Dept Neurosurg, Affiliated Hosp 2, Harbin 150086, Peoples R China

[16] Tianjin Med Univ Gen Hosp, Dept Neurosurg, Tianjin 300052, Peoples R China

[17] Capital Med Univ, Beijing Tiantan Hosp, Dept Radiat Oncol, Beijing 100070, Peoples R China

[18] Chinese Peoples Liberat Army Gen Hosp, Dept Neurosurg, Beijing 100853, Peoples R China

[19] Cent South Univ, Xiangya Hosp, Dept Neurosurg, Changsha 410008, Hunan, Peoples R China

[20] Gen Hosp Southern Theatre Command, Dept Neurosurg, Guangzhou 510010, Peoples R China

[21] Capital Med Univ, San Bo Brain Hosp, Dept Neurosurg, Beijing 100093, Peoples R China

[22] China Med Univ, Dept Neurosurg, Affiliated Hosp 1, Shenyang 110001, Peoples R China

[23] Sun Yat Sen Univ, Dept Neurosurg, Canc Ctr, Guangzhou 510060, Peoples R China

[24] Capital Med Univ, San Bo Brain Hosp, Dept Pathol, Beijing 100093, Peoples R China

[25] Zhengzhou Univ, Dept Neurosurg, Affiliated Hosp 1, Zhengzhou 450052, Peoples R China

[26] Peoples Liberat Army Gen Hosp, Dept Neurosurg, Med Ctr 4, Beijing 100048, Peoples R China

[27] Peoples Liberat Army Gen Hosp, Dept Neurosurg, Med Ctr 7, Beijing 100700, Peoples R China

[28] Army Med Univ, Xinqiao Hosp, Dept Neurosurg, Chongqing 400038, Peoples R China

[29] Air Force Med Univ, Tangdu Hosp, Dept Neurosurg, Xian 710038, Peoples R China

[30] Soochow Univ, Dept Neurosurg, Med Coll, Suzhou 215123, Peoples R China

[31] Gen Hosp Cent Theatre Command, Dept Neurosurg, Wuhan 430070, Peoples R China

来源：

CANCER LETTERS | 2021年 / 499卷

基金：

中国国家自然科学基金;

关键词：

Molecular diagnostics; Surgery; Chemoradiation; Immune therapy; Target therapy; NEWLY-DIAGNOSED GLIOBLASTOMA; RANDOMIZED PHASE-II; TERT PROMOTER MUTATIONS; LOW-GRADE GLIOMAS; BRAIN-TUMORS; DOUBLE-BLIND; EUROPEAN ASSOCIATION; RESPONSE ASSESSMENT; RADIATION-THERAPY; TEMOZOLOMIDE;

D O I：

10.1016/j.canlet.2020.10.050

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

To follow the revision of the fourth edition of WHO classification and the recent progress on the management of diffuse gliomas, the joint guideline committee of Chinese Glioma Cooperative Group (CGCG), Society for Neuro-Oncology of China (SNO-China) and Chinese Brain Cancer Association (CBCA) updated the clinical practice guideline. It provides recommendations for diagnostic and management decisions, and for limiting unnecessary treatments and cost. The recommendations focus on molecular and pathological diagnostics, and the main treatment modalities of surgery, radiotherapy, and chemotherapy. In this guideline, we also integrated the results of some clinical trials of immune therapies and target therapies, which we think are ongoing future directions. The guideline should serve as an application for all professionals involved in the management of patients with adult diffuse glioma and also a source of knowledge for insurance companies and other institutions involved in the cost regulation of cancer care in China and other countries.

引用

页码：60 / 72

页数：13

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