Gas chromatographic method for the determination of toluidines in spiked urine samples

被引：5

作者：

Jodynis-Liebert, J ^{[1
]}

Bennasir, HH ^{[1
]}

机构：

[1] Karol Marcinkowski Univ Med Sci, Dept Toxicol, PL-60631 Poznan, Poland

来源：

JOURNAL OF CHROMATOGRAPHY B | 2000年 / 738卷 / 02期

关键词：

toluidines; heptafluorobutyric anhydride;

D O I：

10.1016/S0378-4347(99)00545-9

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A capillary gas-chromatographic method was developed for the analysis of a mixture of toluidines in urine. The method is based on the extraction of toluidines with toluene and derivatisation with heptafluorobutyric anhydride to form a product for electron capture detection. The procedure gave a Linear response at concentrations of 0.02-0.20 mu g/ml with sufficient reproducibility. The method is simple, requires little sample pretreatment and is being considered for biomonitoring workers exposed to toluidines. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：427 / 430

页数：4

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