A case of progressive apraxia of speech and non-fluent aphasia

A 67-year-old female presented with a progressive deficit over a 2-2 1/2-year period characterized by apraxia of speech and mild non-fluent aphasia. Mild neuropsychological impairments were incompatible with the typical clinical syndrome of dementia. Mild right upper extremity motor impairment and SPECT findings were localizable to the left hemisphere. There was no identifiable cause for the progressive deficits in motor speech and expressive language. The patient's deficit appears to represent a variant of the recently described clinical presentation of progressive motor speech compromise.