Central nervous system prophylaxis in haematological malignancies

被引：15
|
作者：
Wellwood, J [1 ]
Taylor, K [1 ]
机构：
[1] Mater Hosp, Dept Haematol, Brisbane, Qld 4101, Australia
来源：
INTERNAL MEDICINE JOURNAL | 2002年 / 32卷 / 5-6期
关键词：
central nervous system; cranial irradiation; high-dose methotrexate; leukaemia; lymphoma; prophylaxis;
D O I：
10.1046/j.1445-5994.2002.00214.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Given the poor prognosis of central nervous system (CNS) involvement in haematological malignancies, management is directed towards prevention. CNS prophylaxis may take the form of intrathecal therapy, cranial irradiation, systemic therapy or some combination of these. The toxicity of these methods is an important consideration. A risk-orientated approach to the delivery of CNS prophylaxis in each disorder is required.
引用
收藏
页码：252 / 258
页数：7
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