Herpetic anterior uveitis following Pfizer-BioNTech coronavirus disease 2019 vaccine: two case reports

被引:9
作者
Ortiz-Egea, Jose Manuel [1 ]
Gomez Sanchez, Cristina [1 ]
Lopez-Jimenez, Andres [2 ]
Diego Navarro, Olga [1 ]
机构
[1] Complejo Hosp Univ Albacete, Ophthalmol Dept, Albacete, Spain
[2] Hosp Gen Univ Reina Sofia Murcia, Ophthalmol Dept, Murcia, Spain
关键词
SARS-CoV2; COVID-19; vaccines; Herpes zoster; Uveitis anterior; Inflammation; RAT MODELS; REACTIVATION;
D O I
10.1186/s13256-022-03350-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose To describe two cases of herpetic anterior uveitis after inoculation of the first dose of Pfizer-BioNTech coronavirus disease 2019 vaccine. Methods Case 1: a healthy 92-year-old Caucasian woman developed symptomatic unilateral anterior uveitis for 3 days after Pfizer-BioNTech coronavirus disease 2019 vaccination (Pfizer Inc.). The episode fully resolved with topical and oral antiviral treatment. Case 2: a previously healthy 85-year-old Caucasian woman with left hemicranial signs of herpes zoster infection, associated with herpetic keratouveitis for 3 days after Pfizer-BioNTech coronavirus disease 2019 vaccination. Treatment with topical antibiotics and both oral and topical antiherpetic medication was administered, and she recovered successfully in 5 weeks. Conclusion Clinicians should be aware of the possibility of eye inflammation in the form of herpetic reactivation after coronavirus disease 2019 vaccination.
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页数:5
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