Microwave promoted one-pot synthesis of 2-aryl substituted 1,3,4-oxadiazoles and 1,2,4-oxadiazole derivatives using Al3+-K10 clay as a heterogeneous catalyst

被引：30

作者：

Suresh, Dhanusu ^{[1
]}

Kanagaraj, Kuppusamy ^{[1
]}

Pitchumani, Kasi ^{[1
,2
]}

机构：

[1] Madurai Kamaraj Univ, Sch Chem, Madurai 625021, Tamil Nadu, India

[2] Madurai Kamaraj Univ, Sch Chem, Ctr Green Chem, Madurai 625021, Tamil Nadu, India

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 27期

关键词：

K10-montmorillonite; 1,3,4-Oxadiazoles; 1,2,4-Oxadiazoles; One-pot solvent-free synthesis; Green protocol; POLYMER-SUPPORTED REAGENTS; ONE-STEP SYNTHESIS; SOLVENT-FREE; EFFICIENT; INHIBITORS; ACID; DISCOVERY; ZEOLITE; DESIGN;

D O I：

10.1016/j.tetlet.2014.05.004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient, inexpensive method is developed for the one-pot synthesis of 2-aryl substituted 1,3,4-oxadiazoles and 1,2,4-oxadiazoles starting from acid hydrazides and trimethyl orthoformate under solvent-free, microwave conditions using a reusable Al3+-K10 montmorillonite clay as a heterogeneous catalyst. The novelty of the present study lies in the synthesis of oxadiazole and benzimidazole moieties in a onepot process in high yield from easily available precursors and catalysts under mild conditions. [GRAPHICS] (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：3678 / 3682

页数：5

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