Drug delivery systems .2. Camptothecin 20-O-poly(ethylene glycol)ester transport forms

被引：95

作者：

Greenwald, RB

Pendri, A

Conover, C

Gilbert, C

Yang, R

Xia, J

机构：

[1] Enzon Inc., Piscataway, NJ 08854-3969

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1996年 / 39卷 / 10期

关键词：

D O I：

10.1021/jm9600555

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：1938 / 1940

页数：3

共 13 条

[1]

BUNDGAARD H, 1986, BIOREVERSIBLE DERIVA, P49

[2] THE STRUCTURAL BASIS OF CAMPTOTHECIN INTERACTIONS WITH HUMAN SERUM-ALBUMIN - IMPACT ON DRUG STABILITY [J].

BURKE, TG ;

MI, ZH .

JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (01) :40-46

[3]

Garzon-Aburbeh A., 1990, [No title captured], Patent No. 4943579

[4] Drug delivery systems: Water soluble taxol 2'-poly(ethylene glycol) ester prodrugs - Design and in vivo effectiveness [J].

Greenwald, RB ;

Gilbert, CW ;

Pendri, A ;

Conover, CD ;

Xia, J ;

Martinez, A .

JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (02) :424-431

[5] MODIFICATION OF THE HYDROXY LACTONE RING OF CAMPTOTHECIN - INHIBITION OF MAMMALIAN TOPOISOMERASE-I AND BIOLOGICAL-ACTIVITY [J].

HERTZBERG, RP ;

CARANFA, MJ ;

HOLDEN, KG ;

JAKAS, DR ;

GALLAGHER, G ;

MATTERN, MR ;

MONG, SM ;

BARTUS, JO ;

JOHNSON, RK ;

KINGSBURY, WD .

JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (03) :715-720

[6]

JAXEL C, 1989, CANCER RES, V49, P1465

[7] SYNTHESIS AND ANTITUMOR-ACTIVITY OF NOVEL WATER-SOLUBLE DERIVATIVES OF CAMPTOTHECIN AS SPECIFIC INHIBITORS OF TOPOISOMERASE-I [J].

LUZZIO, MJ ;

BESTERMAN, JM ;

EMERSON, DL ;

EVANS, MG ;

LACKEY, K ;

LEITNER, PL ;

MCINTYRE, G ;

MORTON, B ;

MYERS, PL ;

PEEL, M ;

SISCO, JM ;

STERNBACH, DD ;

TONG, WQ ;

TRUESDALE, A ;

UEHLING, DE ;

VUONG, A ;

YATES, J .

JOURNAL OF MEDICINAL CHEMISTRY, 1995, 38 (03) :395-401

[8] DIFFERENTIAL INTERACTIONS OF CAMPTOTHECIN LACTONE AND CARBOXYLATE FORMS WITH HUMAN BLOOD COMPONENTS [J].

MI, ZH ;

BURKE, TG .

BIOCHEMISTRY, 1994, 33 (34) :10325-10336

[9] MARKED INTERSPECIES VARIATIONS CONCERNING THE INTERACTIONS OF CAMPTOTHECIN WITH SERUM ALBUMINS - A FREQUENCY-DOMAIN FLUORESCENCE SPECTROSCOPIC STUDY [J].

MI, ZH ;

BURKE, TG .

BIOCHEMISTRY, 1994, 33 (42) :12540-12545

[10]

POTMESIL M, 1994, CANCER RES, V54, P1431

← 1 2 →