18F-FDG PET/CT in Tumefactive Multiple Sclerosis

被引：15

作者：

Maffione, Anna Margherita ^{[1
]}

Rampin, Lucia ^{[1
]}

Grassetto, Gaia ^{[1
]}

L'Erario, Roberto ^{[2
]}

Colletti, Patrick M. ^{[3
]}

Rubello, Domenico ^{[1
]}

机构：

[1] Santa Maria Misericordia Hosp, Dept Nucl Med, PET Unit, I-45100 Rovigo, Italy

[2] Santa Maria Misericordia Hosp, Dept Neurol, I-45100 Rovigo, Italy

[3] Univ So Calif, Dept Radiol, Los Angeles, CA USA

来源：

CLINICAL NUCLEAR MEDICINE | 2014年 / 39卷 / 08期

关键词：

PET; multiple sclerosis; MRI; FDG; active plaque; LESIONS;

D O I：

10.1097/RLU.0000000000000427

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A 35-year-old man underwent contrast-enhanced MRI and F-18-FDG PET/CT for acute peripheral paresthesia, vision loss, muscle weakness, and difficulty walking. T2-weighted MRI demonstrated multiple bright periventricular supratentorial and infratentorial white matter lesions, including 2 with nodularity. Both nodular lesions showed moderate focal FDG uptake (SUVmax, 6.9 in both cases). Cerebrospinal fluid analysis showed increased levels of immunocytes and oligoclonal antibody bands. A diagnosis of acute onset tumefactive multiple sclerosis was made.

引用

页码：750 / 751

页数：2

共 8 条

[1] PATHOLOGY, HISTOCHEMISTRY AND IMMUNOCYTOCHEMISTRY OF LESIONS IN ACUTE MULTIPLE-SCLEROSIS [J].

ADAMS, CWM ;

POSTON, RN ;

BUK, SJ .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 1989, 92 (2-3) :291-306

[2] Clinical and radiological characteristics of tumefactive demyelinating lesions: follow-up study [J].

Altintas, A. ;

Petek, B. ;

Isik, N. ;

Terzi, M. ;

Bolukbasi, F. ;

Tavsanli, M. ;

Saip, S. ;

Boz, C. ;

Aydin, T. ;

Arici-Duz, O. ;

Ozer, F. ;

Siva, A. .

MULTIPLE SCLEROSIS JOURNAL, 2012, 18 (10) :1448-1453

[3] High-resolution fluorodeoxyglucose positron emission tomography shows both global and regional cerebral hypometabolism in multiple sclerosis [J].

Bakshi, R ;

Miletich, RS ;

Kinkel, PR ;

Emmet, ML ;

Kinkel, WR .

JOURNAL OF NEUROIMAGING, 1998, 8 (04) :228-234

[4]

Chen W, 2006, J NUCL MED, V47, P904

[5] The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis - Identification and characterization of the primary demyelinating lesion [J].

Gay, FW ;

Drye, TJ ;

Dick, GWA ;

Esiri, MM .

BRAIN, 1997, 120 :1461-1483

[6] Positron emission tomography imaging in multiple sclerosis-current status and future applications [J].

Kiferle, L. ;

Politis, M. ;

Muraro, P. A. ;

Piccini, P. .

EUROPEAN JOURNAL OF NEUROLOGY, 2011, 18 (02) :226-231

[7]

Lakhanpal SK, 1999, MAGNETIC RESONANCE I

[8]

Niccolini F, 2014, CLIN NUCL MED

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