Controllable geometry-mediated droplet fission using "off-the-shelf" capillary microfluidics device

被引:10
作者
Wang, Yong [1 ]
Wu, Ping [1 ]
Luo, Zhaofeng [1 ]
Li, Yuting [1 ]
Liao, Meixiang [1 ]
Li, Yue [1 ]
He, Liqun [1 ]
机构
[1] Univ Sci & Technol China, Dept Thermal Sci & Energy Engn, Hefei 230027, Anhui, Peoples R China
来源
RSC ADVANCES | 2014年 / 4卷 / 59期
关键词
PROTEIN CRYSTALLIZATION; SINGLE-CELLS; DIGITAL PCR; GENERATION; EMULSIONS; ENCAPSULATION; SYSTEM;
D O I
10.1039/c4ra04569f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We describe "off-the-shelf" capillary microfluidic devices for droplet fission. The cheap and simple commercial capillary adapters are characterized by perfect sealing, easy assembly and convenient cleaning. Primary droplets, bigger than 65 mu m, without being plugs, can be split into uniform daughter droplets (15-170 mu m) to obtain smaller droplets and increase their concentration. The relative size of daughter droplets can be easily controlled by adjusting the length of the glass capillary tube.
引用
收藏
页码:31184 / 31187
页数:4
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