Synthesis of Some Substituted Pyrazolopyrimidine Derivatives: An Environmentally Benign Approach

被引：8

作者：

Pathak, Arpit Kumar ^{[1
]}

Gupta, Sharoni ^{[1
]}

Punjabi, Pinki B. ^{[1
]}

Ameta, Garima ^{[1
]}

Ameta, Chetna ^{[1
]}

机构：

[1] ML Sukhadia Univ, Univ Coll Sci, Dept Chem, Microwave Synth Lab, Udaipur 313001, Rajasthan, India

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2019年 / 56卷 / 07期

关键词：

MICROWAVE-ASSISTED SYNTHESIS; IONIC LIQUIDS; PYRAZOLES; SOLVENTS; MOIETY;

D O I：

10.1002/jhet.3587

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyrazolopyrimidines constitute a medicinally important class of heterocyclic compounds. Herein, we report an efficient and environmentally benign method for the synthesis of pyrazolo[3,4-d]pyrimidin-3-ones from 2,4-dinitrophenylhydrazine and diethyl malonate under microwave irradiation in 1,3-dibutylimidazolium bromide ionic liquid. The synthesized compounds were analyzed by elemental analysis and standard spectroscopic techniques. The compounds were screened for their antibacterial and antifungal activities.

引用

收藏

页码：2056 / 2062

页数：7

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