Cytogenetic monitoring of nuclear workers occupationally exposed to ionising radiation

被引:6
|
作者
Griciene, B. [1 ,2 ]
Slapsyte, G. [2 ]
Mierauskiene, J. [2 ]
机构
[1] Vilnius State Univ, Dept Radiol Nucl Med & Phys Med, Fac Med, LT-08661 Vilnius, Lithuania
[2] Vilnius State Univ, Fac Nat Sci, Dept Bot & Genet, LT-03101 Vilnius, Lithuania
关键词
POWER-PLANT WORKERS; INDUCED CHROMOSOME-ABERRATIONS; PERIPHERAL-BLOOD LYMPHOCYTES; IN-HOSPITAL WORKERS; FREQUENCY; POPULATIONS; EXPOSURES; DOSIMETRY; DAMAGE; RAYS;
D O I
10.1093/rpd/ncu124
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Chromosome aberration (CA) analysis using Giemsa techniques was performed in blood lymphocytes of 84 nuclear workers with cumulative doses of 1-632 mSv during employment periods of 1-25 y. The control group comprised 82 healthy male donors. An estimated CA frequency in the total radiation-exposed group was significantly higher when compared with the controls (2.27 vs. 1.76 CA/100 cells, p < 0.05). CA analyses revealed no significant differences between workers with external gamma radiation exposure and the controls (1.60 vs. 1.76 CA/100 cells, p > 0.05). However, significant increase in the total CA frequency was determined in workers with additional internal exposure (2.54 CA/100 cells, p < 0.05) and those with registered neutron doses (2.95 CA/100 cells, p < 0.01). No correlation was found between CA frequency and occupational exposure dose. Borderline significant correlation was found between duration of employment and total CA (r = 0.218, p = 0.046, Fig. 2) and chromosome-type aberration (r = 0.265, p = 0.015) frequency.
引用
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页码:10 / 19
页数:10
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