Cardiac Sarcoidosis

被引:30
作者
Birnie, David [1 ]
Ha, Andrew C. T. [2 ]
Gula, Lorne J. [3 ]
Chakrabarti, Santabhanu [4 ]
Beanlands, Rob S. B. [1 ]
Nery, Pablo [1 ]
机构
[1] Univ Ottawa, Inst Heart, Div Cardiol, Ottawa, ON K1Y 4W7, Canada
[2] Univ Toronto, Univ Hlth Network, Peter Munk Cardiac Ctr, Dept Med, Toronto, ON M5G 2C4, Canada
[3] London Hlth Sci Ctr, Div Cardiol, London, ON N6A 5A5, Canada
[4] Univ British Columbia, Dept Med, Div Cardiol, Vancouver, BC V6E 1M7, Canada
关键词
Cardiac sarcoidosis; Clinically silent; Clinically manifest; Atrioventricular block; Ventricular arrhythmias; Heart failure; Sudden cardiac death; POSITRON-EMISSION-TOMOGRAPHY; COLLEGE-OF-CARDIOLOGY; VENTRICULAR-TACHYCARDIA; ENDOMYOCARDIAL BIOPSY; CORTICOSTEROID-THERAPY; ATRIOVENTRICULAR-BLOCK; MYOCARDIAL INVOLVEMENT; CONSENSUS STATEMENT; HEART-ASSOCIATION; STEROID-THERAPY;
D O I
10.1016/j.ccm.2015.08.008
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Studies suggest clinically manifest cardiac involvement occurs in 5% of patients with pulmonary/systemic sarcoidosis. The principal manifestations of cardiac sarcoidosis (CS) are conduction abnormalities, ventricular arrhythmias, and heart failure. Data indicate that a 20% to 25% of patients with pulmonary/systemic sarcoidosis have asymptomatic (clinically silent) cardiac involvement. An international guideline for the diagnosis and management of CS recommends that patients be screened for cardiac involvement. Most studies suggest a benign prognosis for patients with clinically silent CS. Immunosuppression therapy is advocated for clinically manifest CS. Device therapy, with implantable cardioverter defibrillators, is recommended for some patients.
引用
收藏
页码:657 / +
页数:13
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