B-type natriuretic peptide is related to histological skeletal muscle abnormalities in patients with chronic heart failure

被引：8

作者：

Larsen, Alf Inge ^{[1
,2
]}

Skadberg, Oyvind ^{[3
]}

Aarsland, Torbjorn ^{[4
]}

Kvaloy, Jan Terje ^{[5
,6
]}

Lindal, Sigurd ^{[7
]}

Omland, Torbjorn ^{[8
]}

Dickstein, Kenneth ^{[1
,2
]}

机构：

[1] Stavanger Univ Hosp, Dept Cardiol, N-4001 Stavanger, Norway

[2] Univ Bergen, Inst Internal Med, Bergen, Norway

[3] Stavanger Univ Hosp, Div Biochem, N-4001 Stavanger, Norway

[4] Stavanger Hlth Res, Stavanger, Norway

[5] Univ Stavanger, Dept Math & Nat Sci, Stavanger, Norway

[6] Stavanger Univ Hosp, Div Res & Human Resources, N-4001 Stavanger, Norway

[7] Univ Tromso Hosp, Dept Pathol, Tromso, Norway

[8] Univ Oslo, Fac Div Akershus Univ Hosp, Oslo, Norway

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2009年 / 136卷 / 03期

关键词：

Heart failure; BNP; ANP; Exercise; Skeletal muscle histology; Roundness; EXERCISE; MORPHOLOGY; ISCHEMIA; MEN;

D O I：

10.1016/j.ijcard.2008.04.085

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This study examined the potential association between skeletal muscle histological findings and circulating levels of N-terminal Atrial natriuretic peptide (NT-proANP) and N-terminal B-type natriuretic peptide (NT-proBNP) at rest and during exercise in patients with moderate chronic heart failure. We report a significant correlation between muscle fibre roundness, defined as ratio of fibre perimeter squared to fibre area, and plasma levels of N-BNP. This finding suggests that the degree of intrafibrillar edema is related to the secretion of NT-proBNP. (C) 2008 Published by Elsevier Ireland Ltd.

引用

页码：358 / 362

页数：6

共 15 条

[1] SKELETAL-MUSCLE DAMAGE DURING TOURNIQUET-INDUCED ISCHEMIA - THE INITIAL STEP TOWARDS ATROPHY AFTER ORTHOPEDIC-SURGERY
APPELL, HJ
GLOSER, S
DUARTE, JAR
ZELLNER, A
SOARES, JMC
[J]. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY AND OCCUPATIONAL PHYSIOLOGY, 1993, 67 (04): : 342 - 347
[2] ENGEL AG, 1986, MYOLOGY
[3] Focal brain edema and natriuretic peptides in patients with subarachnoid hemorrhage
Fukui, S
Katoh, H
Tsuzuki, N
Ishihara, S
Otani, N
Ooigawa, H
Toyooka, T
Ohnuki, A
Miyazawa, T
Nawashiro, H
Shima, K
[J]. JOURNAL OF CLINICAL NEUROSCIENCE, 2004, 11 (05) : 507 - 511
[4] COMPARATIVE VASOACTIVE EFFECTS OF NATIVE AND SYNTHETIC ATRIAL NATRIURETIC FACTOR (ANF)
GARCIA, R
THIBAULT, G
NUTT, RF
CANTIN, M
GENEST, J
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 119 (02) : 685 - 688
[5] Osmoregulation of atrial myocytic ANP release:: osmotransduction via cross-talk between L-type Ca2+ channel and SR Ca2+ release
Jin, JY
Wen, JF
Li, D
Cho, KW
[J]. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2004, 287 (05) : R1101 - R1109
[6] Effect of exercise training on skeletal muscle fibre characteristics in men with chronic heart failure. Correlation between skeletal muscle alterations, cytokines and exercise capacity
Larsen, AI
Lindal, S
Aukrust, P
Toft, I
Aarsland, T
Dickstein, K
[J]. INTERNATIONAL JOURNAL OF CARDIOLOGY, 2002, 83 (01) : 25 - 32
[7] Prognostic usefulness of an increase of N-terminal proatrial natriuretic peptide during exercise in patients with chronic heart failure
Larsen, AI
Hall, C
Aukrust, P
Aarsland, T
Faris, P
Dickstein, K
[J]. AMERICAN JOURNAL OF CARDIOLOGY, 2003, 92 (01) : 91 - 94
[8] Assessing the effect of exercise training in men with heart failure - Comparison of maximal, submaximal and endurance exercise protocols
Larsen, AI
Aarsland, T
Kristiansen, M
Haugland, A
Dickstein, K
[J]. EUROPEAN HEART JOURNAL, 2001, 22 (08) : 684 - 692
[9] Lindal Sigurd, 1994, Tidsskrift for den Norske Laegeforening, V114, P928
[10] ABNORMALITIES OF SKELETAL-MUSCLE IN PATIENTS WITH CHRONIC HEART-FAILURE
LIPKIN, DP
JONES, DA
ROUND, JM
POOLEWILSON, PA
[J]. INTERNATIONAL JOURNAL OF CARDIOLOGY, 1988, 18 (02) : 187 - 195

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