Characteristics and antecedents of progressive multifocal leukoencephalopathy in an insured population

被引：30

作者：

Eng, P. M.

Turnbull, B. R.

Cook, S. F.

Davidson, J. E.

Kurth, T.

Seeger, J. D.

机构：

[1] i3 Drug Safety, Riverside Ctr, Auburndale, MA 02466 USA

[2] GlaxoSmithKline Inc, Res Triangle Pk, NC USA

[3] GlaxoSmithKline Inc, Harlow, Essex, England

[4] Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Med,Div Aging, Boston, MA 02115 USA

[5] Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Med,Div Prevent Med, Boston, MA 02115 USA

[6] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA

来源：

NEUROLOGY | 2006年 / 67卷 / 05期

关键词：

D O I：

10.1212/01.wnl.0000233918.21986.9c

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Based on health insurance claims from a large U.S. health insurer, the authors identified 44 progressive multifocal leukoencephalopathy (PML) cases from 2002 through 2004 and described their characteristics, including antecedent diagnoses and treatments as well as survival. Immunosuppressive conditions such as HIV/AIDS, rather than potentially immunosuppressive treatments, were the main antecedents of PML. A lower mortality was observed among PML patients whose antecedent diagnosis was HIV/AIDS, the majority of whom received highly active antiretroviral therapy.

引用

页码：884 / 886

页数：3

共 10 条

[1] Clinical epidemiology and survival of progressive multifocal leukoencephalopathy in the era of highly active antiretroviral therapy: Data from the Italian Registry Investigative Neuro AIDS (IRINA) [J].