MajesTEC-7: A Phase 3, Randomized Study of Teclistamab plus Daratumumab plus Lenalidomide (Tec-DR) Versus Daratumumab plus Lenalidomide plus Dexamethasone (DRd) in Patients with Newly Diagnosed Multiple Myeloma Who Are Either Ineligible or Not Intended for Autologous Stem Cell Transplant

被引：22

作者：

Krishnan, Amrita Y. ^{[1
]}

Manier, Salomon ^{[2
]}

Terpos, Evangelos ^{[3
]}

Usmani, Saad ^{[4
]}

Khan, Josephine ^{[5
]}

Pearson, Rachel ^{[5
]}

Girgis, Suzette ^{[6
]}

Guo, Yue ^{[6
]}

McAleer, Dana ^{[6
]}

Olyslager, Yunsi ^{[7
]}

Kampfenkel, Tobias ^{[8
]}

van de Donk, Niels W. C. J. ^{[9
]}

机构：

[1] City Hope Comprehens Canc Ctr, Duarte, CA USA

[2] Univ Lille, Lille, France

[3] Univ Athens, Athens, Greece

[4] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA

[5] Janssen Res & Dev, High Wycombe, Bucks, England

[6] Janssen Res & Dev, Spring House, PA USA

[7] Janssen Res & Dev, Beerse, Belgium

[8] Janssen Res & Dev, Neuss, Germany

[9] Vrije Univ Amsterdam, Amsterdam Univ Med Ctr, Amsterdam, Netherlands

来源：

BLOOD | 2022年 / 140卷

关键词：

D O I：

10.1182/blood-2022-160173

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：10148 / 10149

页数：2

共 50 条

[21] Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Treatment in Patients With Newly Diagnosed Multiple Myeloma After Frontline Transplant: A Multicenter, Randomized, Phase 3 Study (AURIGA) [J].

Lin, Thomas ;

Hampras, Shalaka ;

Krey, Ryan ;

Pei, Huiling ;

Qi, Ming ;

Krevvata, Maria ;

Kane, Colleen ;

Lutska, Yana ;

Ryland, Katherine ;

Chiu, Chris ;

Ukropec, Jon ;

Shah, Nina .

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2019, 19 (10) :E199-E199

[22] MajesTEC-3: Randomized, phase 3 study of teclistamab plus daratumumab versus investigator's choice of daratumumab, pomalidomide, and dexamethasone or daratumumab, bortezomib, and dexamethasone in patients with relapsed/refractory multiple myeloma. [J].

Mateos, Maria-Victoria ;

Bahlis, Nizar J. ;

Costa, Luciano J. ;

Perrot, Aurore ;

Pei, Lixia ;

Rubin, Maria L. ;

Lantz, Kristen ;

Sun, Weili ;

Jaffe, Mindy ;

Kobos, Rachel ;

Nooka, Ajay K. .

JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)

[23] Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) in Transplant-Ineligible Patients (Pts) with Newly Diagnosed Multiple Myeloma (NDMM): Clinical Assessment of Key Subgroups of the Phase 3 Maia Study [J].

Moreau, Philippe ;

Facon, Thierry ;

Usmani, Saad ;

Bahlis, Nizar Jacques ;

Raje, Noopur ;

Plesner, Torben ;

Orlowski, Robert Z. ;

Basu, Supratik ;

Nahi, Hareth ;

Hulin, Cyrille ;

Quach, Hang ;

Goldschmidt, Hartmut ;

O'Dwyer, Michael ;

Perrot, Aurore ;

Venner, Christopher P. ;

Weisel, Katja ;

Tiab, Mourad ;

Macro, Margaret ;

Frenzel, Laurent ;

Leleu, Xavier ;

Pei, Huiling ;

Krevvata, Maria ;

Carson, Robin ;

Borgsten, Fredrik ;

Kumar, Shaji K. .

BLOOD, 2022, 140 :7297-7300

[24] Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) in Transplant-ineligible Patients (Pts) With Newly Diagnosed Multiple Myeloma (NDMM): Clinical Assessment of Key Subgroups of the Phase 3 MAIA Study [J].

Moreau, P. ;

Facon, T. ;

Usmani, S. Z. ;

Bahlis, N. ;

Raje, N. ;

Plesner, T. ;

Orlowski, R. Z. ;

Basu, S. ;

Nahi, H. ;

Hulin, C. ;

Quach, H. ;

Goldschmidt, H. ;

O'Dwyer, M. ;

Perrot, A. ;

Venner, C. P. ;

Weisel, K. ;

Tiab, M. ;

Macro, M. ;

Frenzel, L. ;

Leleu, X. ;

Wang, G. ;

Krevvata, M. ;

Carson, R. ;

Borgsten, F. ;

Kumar, S. K. .

ONCOLOGY RESEARCH AND TREATMENT, 2023, 46 :238-238

[25] Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) in Transplant-ineligible Patients (Pts) With Newly Diagnosed Multiple Myeloma (NDMM): Clinical Assessment of Key Subgroups of the Phase 3 MAIA Study [J].

Moreau, P. ;

Facon, T. ;

Usmani, S. Z. ;

Bahlis, N. ;

Raje, N. ;

Plesner, T. ;

Orlowski, R. Z. ;

Basu, S. ;

Nahi, H. ;

Hulin, C. ;

Quach, H. ;

Goldschmidt, H. ;

O'Dwyer, M. ;

Perrot, A. ;

Venner, C. P. ;

Weisel, K. ;

Tiab, M. ;

Macro, M. ;

Frenzel, L. ;

Leleu, X. ;

Pei, H. ;

Krevvata, M. ;

Carson, R. ;

Borgsten, F. ;

Kumar, S. K. .

ONCOLOGY RESEARCH AND TREATMENT, 2023, 46 :316-317

[26] A plain language summary of the PERSEUS study of daratumumab plus bortezomib, lenalidomide, and dexamethasone for treating newly diagnosed multiple myeloma [J].

Sonneveld, Pieter ;

Dimopoulos, Meletios A. ;

Boccadoro, Mario ;

Quach, Hang ;

Ho, P. Joy ;

Beksac, Meral ;

Hulin, Cyrille ;

Antonioli, Elisabetta ;

Leleu, Xavier ;

Mangiacavalli, Silvia ;

Perrot, Aurore ;

Cavo, Michele ;

Belotti, Angelo ;

Broijl, Annemiek ;

Gay, Francesca ;

Mina, Roberto ;

van de Donk, Niels W. C. J. ;

Katodritou, Eirini ;

Schjesvold, Fredrik ;

Balari, Anna Sureda ;

Rosinol, Laura ;

Delforge, Michel ;

Roeloffzen, Wilfried ;

Silzle, Tobias ;

Vangsted, Annette ;

Einsele, Hermann ;

Spencer, Andrew ;

Hajek, Roman ;

Jurczyszyn, Artur ;

Lonergan, Sarah ;

Ahmadi, Tahamtan ;

Liu, Yanfang ;

Wang, Jianping ;

Vieyra, Diego ;

van Brummelen, Emilie M. J. ;

Vanquickelberghe, Veronique ;

Sitthi-Amorn, Anna ;

de Boer, Carla J. ;

Carson, Robin ;

Rodriguez-Otero, Paula ;

Blade, Joan ;

Moreau, Philippe .

FUTURE ONCOLOGY, 2024, 20 (38) :3043-3063

[27] Plain language summary of the MAIA study of daratumumab plus lenalidomide and dexamethasone for the treatment of people with newly diagnosed multiple myeloma [J].

Facon, Thierry ;

Kumar, Shaji K. ;

Plesner, Torben ;

Orlowski, Robert Z. ;

Moreau, Philippe ;

Bahlis, Nizar ;

Basu, Supratik ;

Nahi, Hareth ;

Hulin, Cyrille ;

Quach, Hang ;

Goldschmidt, Hartmut ;

Perrot, Aurore ;

Weisel, Katja ;

Raje, Noopur ;

Macro, Margaret ;

Frenzel, Laurent ;

Leleu, Xavier ;

Wang, Jianping ;

Van Rampelbergh, Rian ;

Uhlar, Clarissa M. ;

Vermeulen, Jessica ;

Duran, Joana ;

Borgsten, Fredrik ;

Usmani, Saad Z. .

FUTURE ONCOLOGY, 2023, 19 (13) :887-895

[28] Daratumumab plus lenalidomide, bortezomib and dexamethasone in newly diagnosed multiple myeloma: Analysis of vascular thrombotic events in the GRIFFIN study [J].

Sborov, Douglas W. ;

Baljevic, Muhamed ;

Reeves, Brandi ;

Laubach, Jacob ;

Efebera, Yvonne A. ;

Rodriguez, Cesar ;

Costa, Luciano J. ;

Chari, Ajai ;

Silbermann, Rebecca ;

Holstein, Sarah A. ;

Anderson, Larry D., Jr. ;

Kaufman, Jonathan L. ;

Shah, Nina ;

Pei, Huiling ;

Patel, Sharmila ;

Cortoos, Annelore ;

Bartlett, J. Blake ;

Vermeulen, Jessica ;

Lin, Thomas S. ;

Voorhees, Peter M. ;

Richardson, Paul G. .

BRITISH JOURNAL OF HAEMATOLOGY, 2022, 199 (03) :355-365

[29] MajesTEC-4 (EMN30): A Phase 3 Trial of Teclistamab plus Lenalidomide Versus Lenalidomide Alone As Maintenance Therapy Following Autologous Stem Cell Transplantation in Patients with Newly Diagnosed Multiple Myeloma [J].

Zamagni, Elena ;

Boccadoro, Mario ;

Spencer, Andrew ;

Delforge, Michel ;

Reece, Donna E. ;

Szabo, Agoston Gyula ;

Einsele, Hermann ;

Terpos, Evangelos ;

Schjesvold, Fredrik ;

Bila, Jelena ;

Driessen, Christoph ;

Beksac, Meral ;

Cook, Gordon ;

Rodriguez, Cesar ;

Pei, Lixia ;

Shi, Yingqi ;

Sakabedoyan, Caline ;

Jasielec, Jagaoda ;

Amin, Himal ;

Kobos, Rachel ;

Sonneveld, Pieter ;

Van de Donk, Niels W. C. J. .

BLOOD, 2022, 140 :7289-7291

[30] Daratumumab plus Lenalidomide, Bortezomib & Dexamethasone Improves Depth of Response in Transplant-eligible Newly Diagnosed Multiple Myeloma: GRIFFIN [J].

Voorhees, Peter ;

Kaufman, Jonathan L. ;

Laubach, Jacob ;

Sborov, Douglas ;

Reeves, Brandi ;

Rodriguez, Cesar ;

Chari, Ajai ;

Silbermann, Rebecca ;

Costa, Luciano ;

Anderson, Larry ;

Nathwani, Nitya ;

Shah, Nina ;

Efebera, Yvonne ;

Costello, Caitlin ;

Jakubowiak, Andrzej ;

Wildes, Tanya ;

Orlowski, Robert Z. ;

Shain, Kenneth H. ;

Cowan, Andrew ;

Murphy, Sean ;

Lutska, Yana ;

Pei, Huiling ;

Ukropec, Jon ;

Vermeulen, Jessica ;

de Boer, Carla ;

Hoehn, Daniela ;

Lin, Thomas ;

Richardson, Paul G. .

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2019, 19 (10) :E353-E354

← 1 2 3 4 5 →