MajesTEC-7: A Phase 3, Randomized Study of Teclistamab plus Daratumumab plus Lenalidomide (Tec-DR) Versus Daratumumab plus Lenalidomide plus Dexamethasone (DRd) in Patients with Newly Diagnosed Multiple Myeloma Who Are Either Ineligible or Not Intended for Autologous Stem Cell Transplant

被引：22

作者：

Krishnan, Amrita Y. ^{[1
]}

Manier, Salomon ^{[2
]}

Terpos, Evangelos ^{[3
]}

Usmani, Saad ^{[4
]}

Khan, Josephine ^{[5
]}

Pearson, Rachel ^{[5
]}

Girgis, Suzette ^{[6
]}

Guo, Yue ^{[6
]}

McAleer, Dana ^{[6
]}

Olyslager, Yunsi ^{[7
]}

Kampfenkel, Tobias ^{[8
]}

van de Donk, Niels W. C. J. ^{[9
]}

机构：

[1] City Hope Comprehens Canc Ctr, Duarte, CA USA

[2] Univ Lille, Lille, France

[3] Univ Athens, Athens, Greece

[4] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA

[5] Janssen Res & Dev, High Wycombe, Bucks, England

[6] Janssen Res & Dev, Spring House, PA USA

[7] Janssen Res & Dev, Beerse, Belgium

[8] Janssen Res & Dev, Neuss, Germany

[9] Vrije Univ Amsterdam, Amsterdam Univ Med Ctr, Amsterdam, Netherlands

来源：

BLOOD | 2022年 / 140卷

关键词：

D O I：

10.1182/blood-2022-160173

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：10148 / 10149

页数：2

共 50 条

[11] Daratumumab plus bortezomib, lenalidomide and dexamethasone for transplant-ineligible or transplant-deferred newly diagnosed multiple myeloma: the randomized phase 3 CEPHEUS trial [J].

Usmani, Saad Z. ;

Facon, Thierry ;

Hungria, Vania ;

Bahlis, Nizar J. ;

Venner, Christopher P. ;

Braunstein, Marc ;

Pour, Ludek ;

Marti, Josep M. ;

Basu, Supratik ;

Cohen, Yael C. ;

Matsumoto, Morio ;

Suzuki, Kenshi ;

Hulin, Cyrille ;

Grosicki, Sebastian ;

Legiec, Wojciech ;

Beksac, Meral ;

Maiolino, Angelo ;

Takamatsu, Hiroyuki ;

Perrot, Aurore ;

Turgut, Mehmet ;

Ahmadi, Tahamtan ;

Liu, Weiping ;

Wang, Jianping ;

Chastain, Katherine ;

Vermeulen, Jessica ;

Krevvata, Maria ;

Lopez-Masi, Lorena ;

Carey, Jodi ;

Rowe, Melissa ;

Carson, Robin ;

Zweegman, Sonja .

NATURE MEDICINE, 2025, 31 (04) :1195-1202

[12] Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) in Patients with Newly Diagnosed Multiple Myeloma (NDMM) Ineligible for Transplant: Updated Analysis of Maia [J].

Bahlis, Nizar ;

Facon, Thierry ;

Usmani, Saad Z. ;

Kumar, Shaji K. ;

Plesner, Torben ;

Orlowski, Robert Z. ;

Touzeau, Cyrille ;

Basu, Supratik ;

Nahi, Hareth ;

Hulin, Cyrille ;

Quach, Hang ;

Goldschmidt, Hartmut ;

O'Dwyer, Michael E. ;

Venner, Christopher P. ;

Weisel, Katja C. ;

Krevvata, Maria ;

Pei, Huiling ;

Wang, Jianping ;

Van Rampelbergh, Rian ;

Ukropec, Jon ;

Uhlar, Clarissa M. ;

Kobos, Rachel ;

Perrot, Aurore .

BLOOD, 2019, 134

[13] Daratumumab plus Lenalidomide/ dexamethasone in transplant-neligible patients with newly diagnosed multiple myeloma: MAIA update [J].

Basu, Supratik ;

Kumar, Shaji K. ;

Moreau, Philippe ;

Bahlis, Nizar ;

Facon, Thierry ;

Plesner, Torben ;

Orlowski, Robert Z. ;

Nahi, Hareth ;

Hulin, Cyrille ;

Quach, Hang ;

Goldschmidt, Hartmut ;

O'Dwyer, Michael ;

Perrot, Aurore ;

Venner, Christopher P. ;

Weisel, Katja ;

Raje, Noopur ;

Tiab, Mourad ;

Macro, Margaret ;

Frenzel, Laurent ;

Leleu, Xavier ;

Pei, Huiling ;

Krevvata, Maria ;

Borgsten, Fredrik ;

Usmani, Saad Z. .

BRITISH JOURNAL OF HAEMATOLOGY, 2023, 201 :17-18

[14] Daratumumab plus Bortezomib/Lenalidomide/ Dexamethasone in Patients With Transplant-ineligible or Transplant-deferred Newly Diagnosed Multiple Myeloma: Results of the Phase 3 CEPHEUS Study [J].

Usmani, Saad Z. ;

Facon, Thierry ;

Hungria, Vania ;

Bahlis, Nizar J. ;

Venner, Christopher P. ;

Braunstein, Marc ;

Pour, Ludek ;

Marti, Josep ;

Basu, Supratik ;

Cohen, Yael C. ;

Matsumoto, Morio ;

Suzuki, Kenshi ;

Hulin, Cyrille ;

Grosicki, Sebastian ;

Legiec, Wojciech ;

Beksac, Meral ;

Maiolino, Angelo ;

Liu, Weiping ;

Wang, Jianping ;

Krevvata, Maria ;

Lopez-Masi, Lorena ;

Carey, Jodi ;

Rowe, Melissa ;

Carson, Robin ;

Zweegman, Sonja .

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2024, 24 :S288-S289

[15] Daratumumab plus Bortezomib/Lenalidomide/Dexamethasone in Transplant Ineligible/ Transplant Deferred Newly Diagnosed MM: Phase 3 CEPHEUS Results [J].

Basu, Supratik ;

Usmani, Saad ;

Facon, Thierry ;

Hungria, Vania ;

Bahlis, Nizar ;

Venner, Christopher ;

Braunstein, Marc ;

Rowe, Melissa ;

Carson, Robin ;

Zweegman, Sonia .

BRITISH JOURNAL OF HAEMATOLOGY, 2025, 206

[16] Updated Analysis of Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) in Patients with Transplant-Ineligible Newly Diagnosed Multiple Myeloma (NDMM): The Phase 3 Maia Study [J].

Kumar, Shaji K. ;

Facon, Thierry ;

Usmani, Saad Z. ;

Plesner, Torben ;

Orlowski, Robert Z. ;

Touzeau, Cyrille ;

Basu, Supratik ;

Bahlis, Nizar J. ;

Goldschmidt, Hartmut ;

O'Dwyer, Michael E. ;

Venner, Christopher P. ;

Weisel, Katja ;

Hulin, Cyrille ;

Karlin, Lionel ;

Preis, Meir ;

Broyl, Annemiek ;

Renwick, William ;

Hansson, Markus ;

Krevvata, Maria ;

Wang, Jianping ;

Van Rampelbergh, Rian ;

Ukropec, Jon ;

Uhlar, Clarissa M. ;

Kobos, Rachel ;

Perrot, Aurore .

BLOOD, 2020, 136

[17] Daratumumab plus lenalidomide/bortezomib/dexamethasone in Black patients with transplant-eligible newly diagnosed multiple myeloma in GRIFFIN [J].

Ajay K. Nooka ;

Jonathan L. Kaufman ;

Cesar Rodriguez ;

Andrzej Jakubowiak ;

Yvonne Efebera ;

Brandi Reeves ;

Tanya Wildes ;

Sarah A. Holstein ;

Larry D. Anderson ;

Ashraf Badros ;

Leyla Shune ;

Ajai Chari ;

Huiling Pei ;

Annelore Cortoos ;

Sharmila Patel ;

J. Blake Bartlett ;

Jessica Vermeulen ;

Thomas S. Lin ;

Paul G. Richardson ;

Peter Voorhees .

Blood Cancer Journal, 12

[18] Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) Alone in Transplant-Ineligible Patients with Newly Diagnosed Multiple Myeloma (NDMM): Updated Analysis of the Phase 3 Maia Study [J].

Kumar, Shaji K. ;

Moreau, Philippe ;

Bahlis, Nizar Jacques ;

Facon, Thierry ;

Plesner, Torben ;

Orlowski, Robert Z. ;

Basu, Supratik ;

Nahi, Hareth ;

Hulin, Cyrille ;

Quach, Hang ;

Goldschmidt, Hartmut ;

O'Dwyer, Michael ;

Perrot, Aurore ;

Venner, Christopher P. ;

Weisel, Katja ;

Raje, Noopur ;

Tiab, Mourad ;

Macro, Margaret ;

Frenzel, Laurent ;

Leleu, Xavier ;

Pei, Huiling ;

Krevvata, Maria ;

Carson, Robin ;

Borgsten, Fredrik ;

Usmani, Saad .

BLOOD, 2022, 140 :10150-10153

[19] Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) Alone in Transplant-ineligible Patients with Newly Diagnosed Multiple Myeloma (NDMM): Updated Analysis of the Phase 3 MAIA Study [J].

Kumar, S. K. ;

Moreau, P. ;

Bahlis, N. ;

Facon, T. ;

Plesner, T. ;

Orlowski, R. Z. ;

Basu, S. ;

Nahi, H. ;

Hulin, C. ;

Quach, H. ;

Goldschmidt, H. ;

O'Dwyer, M. ;

Perrot, A. ;

Venner, C. P. ;

Weisel, K. ;

Raje, N. ;

Tiab, M. ;

Macro, M. ;

Frenzel, L. ;

Leleu, X. ;

Wang, G. ;

Krevvata, M. ;

Carson, R. ;

Borgsten, F. ;

Usmani, S. Z. .

ONCOLOGY RESEARCH AND TREATMENT, 2023, 46 :183-184

[20] Daratumumab plus lenalidomide/bortezomib/dexamethasone in Black patients with transplant-eligible newly diagnosed multiple myeloma in GRIFFIN [J].

Nooka, Ajay K. ;

Kaufman, Jonathan L. ;

Rodriguez, Cesar ;

Jakubowiak, Andrzej ;

Efebera, Yvonne ;

Reeves, Brandi ;

Wildes, Tanya ;

Holstein, Sarah A. ;

Anderson, Larry D., Jr. ;

Badros, Ashraf ;

Shune, Leyla ;

Chari, Ajai ;

Pei, Huiling ;

Cortoos, Annelore ;

Patel, Sharmila ;

Bartlett, J. Blake ;

Vermeulen, Jessica ;

Lin, Thomas S. ;

Richardson, Paul G. ;

Voorhees, Peter .

BLOOD CANCER JOURNAL, 2022, 12 (04)

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