On-line optical imaging of the human brain with 160-ms temporal resolution

被引：183
作者：
Franceschini, MA
Toronov, V
Filiaci, ME
Gratton, E
Fantini, S
机构：
[1] Tufts Univ, Ctr Bioengn, Dept Elect Engn & Comp Sci, Medford, MA 02155 USA
[2] Univ Illinois, Fluorescence Dynam Lab, Urbana, IL 61801 USA
来源：
OPTICS EXPRESS | 2000年 / 6卷 / 03期
关键词：
D O I：
10.1364/OE.6.000049
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
We have developed an instrument for non-invasive optical imaging of the human brain that produces on-line images with a temporal resolution of 160 ms. The imaged quantities are the temporal changes in cerebral oxy-hemoglobin and deoxy-hemoglobin concentrations. We report real-time videos of the arterial pulsation and motor activation recorded on a 4 x 9 cm(2) area of the cerebral cortex in a healthy human subject. This approach to optical brain imaging is a powerful tool for the investigation of the spatial and temporal features of the optical signals collected on the brain. (C)2000 Optical Society of America.
引用
收藏
页码：49 / 57
页数：9
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