Antiandrogenic effect of Striga orobanchioides

被引：21

作者：

Hiremath, SP ^{[1
]}

Badami, S ^{[1
]}

Swamy, HKS ^{[1
]}

Patil, SB ^{[1
]}

Londonkar, RL ^{[1
]}

机构：

[1] GULBARGA UNIV,DEPT ZOOL,GULBARGA 585106,INDIA

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1997年 / 56卷 / 01期

关键词：

D O I：

10.1016/S0378-8741(96)01505-X

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The ethanolic extract of the whole plant of Striga orobanchioides given for 7 days to immature male rats at a dose level of 200 mg/kg body weight caused a significant decrease in the weight of the testes, epididymis, seminal vesicles and the ventral prostate. It also produced degenerative changes of Leydig cells, their nucleus, the seminiferous tubules and a significant decrease in the number of spermatocytes and spermatids. The seminiferous tubules of the treated rats are shrunken and compactly arranged. The antiandrogenic or antispermatogenic effect of the extract is discussed. (C) 1997 Elsevier Science Ireland Ltd.

引用

页码：55 / 60

页数：6

共 11 条

[1] ANTIANDROGENIC EFFECTS OF A FLAVONOID-RICH FRACTION OF VITEX-NEGUNDO SEEDS - A HISTOLOGICAL AND BIOCHEMICAL-STUDY IN DOGS [J].