Unexplored reactivity of 2-oxoaldehydes towards Pictet-Spengler conditions: concise approach to β-carboline based marine natural products

被引：44

作者：

Battini, Narsaiah ^{[1
,2
]}

Padala, Anil K. ^{[1
,2
]}

Mupparapu, Nagaraju ^{[1
,2
]}

Vishwakarma, Ram A. ^{[1
,2
]}

Ahmed, Qazi Naveed ^{[1
,2
]}

机构：

[1] Acad Sci & Innovat Res, New Delhi, India

[2] CSIR Indian Inst Integrat Med, Jammu 180001, India

来源：

RSC ADVANCES | 2014年 / 4卷 / 50期

关键词：

ALKALOIDS; FASCAPLYSIN; ACCESS;

D O I：

10.1039/c4ra01387e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Novel reactions under Pictet-Spengler conditions between tryptophan methyl ester/tryptamine and 2-oxoaldehydes have been developed and successfully utilized for the total synthesis of Merinacarboline (A and B), Eudistomin Y1, Pityriacitrin B, Pityriacitrin, Fascaplysin and analogues.

引用

页码：26258 / 26263

页数：6

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