Nano-CoFe2O4 supported molybdenum as an efficient and magnetically recoverable catalyst for a one-pot, four-component synthesis of functionalized pyrroles

被引:99
作者
Li, Bao-Le [1 ]
Zhang, Mo [2 ]
Hu, Hai-Chuan [1 ]
Du, Xia [2 ]
Zhang, Zhan-Hui [1 ]
机构
[1] Hebei Normal Univ, Coll Chem & Mat Sci, Shijiazhuang 050024, Peoples R China
[2] Hebei Normal Univ, Huihua Coll, Shijiazhuang 050091, Peoples R China
基金
中国国家自然科学基金;
关键词
ENCAPSULATED GAMMA-FE2O3 NANOPARTICLES; HIGHLY SUBSTITUTED PYRROLES; 3-COMPONENT SYNTHESIS; MULTICOMPONENT REACTIONS; SEPARABLE CATALYST; SULFONIC-ACID; CHLORIDE; CYCLIZATION; CORE; NANOCOMPOSITES;
D O I
10.1039/c3nj01368e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel magnetic nanoparticle CoFe2O4 supported Mo([CoFe2O4@SiO2-PrNH2-Mo(acac)(2)]) was prepared and found to be a highly active and efficient catalyst for a one-pot synthesis of polysubstituted pyrroles via four-component reaction of aldehydes, amines, 1,3-dicarbonyl compounds and nitromethane. The easy recovery of the catalyst and reusability, broad substrate scopes, short reaction time, high yields of products and solvent-free conditions make this protocol practical, environmentally friendly and economically attractive.
引用
收藏
页码:2435 / 2442
页数:8
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