Structure and biosynthesis of chrysophysarin A, a plasmodial pigment from the slime mould Physarum polycephalum (Myxomycetes)

被引：28

作者：

Eisenbarth, S ^{[1
]}

Steffan, B ^{[1
]}

机构：

[1] Univ Munich, Inst Organ Chem, D-81377 Munich, Germany

来源：

TETRAHEDRON | 2000年 / 56卷 / 03期

关键词：

slime mould; myxomycetes; Physarum polycephalum; natural products; polyene; imidazole;

D O I：

10.1016/S0040-4020(99)01020-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A yellow optically-active pigment, chrysophysarin A (1), has been isolated from microplasmodia of the slime mould Physarum polycephalum. The structure was established by means of 1D and 2D NMR spectroscopy and mass spectrometry. The absolute configuration was assigned by the synthesis of N-(3,3-dimethylacryloyl) derivatives of (S)- and (R)-leucine and by comparison of the corresponding CD spectra. The biosynthesis of the compound was elucidated by feeding labeled acetate to the plasmodia. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：363 / 365

页数：3

共 11 条

[1]

Daniel J. W., 1964, METHODS CELL PHYSL, V1, P9

[2]

DEIMER KH, 1974, METHOD ORGAN CHEM, P319

[3]

ISHIDA N, 1977, CYTOBIOLOGIE, V15, P269

[4]

Luckner M., 1990, Secondary Metabolism in Microorganisms, Plants and Animals, V3

[5] Action spectrum for sporulation and photoavoidance in the plasmodium of Physarum polycephalum, as modified differentially by temperature and starvation [J].

Nakagaki, T ;

Umemura, S ;

Kakiuchi, Y ;

Ueda, T .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1996, 64 (05) :859-862

[6]

Nowak A, 1998, ANGEW CHEM INT EDIT, V37, P3139, DOI 10.1002/(SICI)1521-3773(19981204)37:22<3139::AID-ANIE3139>3.0.CO

[7]

2-6

[8]

Nowak A, 1997, LIEBIGS ANN-RECL, P1817

[9]

NOWAK A, 1998, ANGEW CHEM, V110, P3341

[10]

Rakoczy L, 1980, BLUE LIGHT SYNDROME, P570

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