Synthesis and promotion angiogenesis effect of chrysin derivatives coupled to NO donors

被引：16

作者：

Peng, Sheng-Ming ^{[1
]}

Zou, Xiao-Qing ^{[1
]}

Ding, Hua-Lan ^{[1
]}

Ding, Yong-Lan ^{[1
]}

Lin, Yuan-Bin ^{[1
]}

机构：

[1] Xiangtan Univ, Coll Chem, Minist Educ, Key Lab Environmentally Friendly Chem & Applicat, Xiangtan 411105, Hunan, Peoples R China

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2009年 / 19卷 / 04期

关键词：

Angiogenesis; Chrysin derivatives; Furazan derivatives; Alkyl nitrate; Couple; TEA POLYPHENOLS; ENDOTHELIAL-CELLS; FLAVONOIDS; RELEASE;

D O I：

10.1016/j.bmcl.2008.12.116

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two types of new chrysin derivatives were prepared by coupling NO donors of alkyl nitrate and furazan derivatives and were fully characterized by H-1 NMR and other techniques. These compounds were tested in human umbilical vein endothelial cells (HUVECs-12) and all the compounds exhibited cell proliferation. Notable effects of promoting angiogenesis were observed for all the modified compounds using chick chorioallantoic membrane (CAM) assay. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：1264 / 1266

页数：3

共 50 条

[41] Ultrasound-promoted copper-catalyzed synthesis of bis-arylselanyl chrysin derivatives with boosted antioxidant and anticancer activities [J].

Fonseca, Sergio F. ;

Padilha, Nathalia B. ;

Thurow, Samuel ;

Roehrs, Juliano A. ;

Savegnago, Lucielli ;

de Souza, Maurice N. ;

Fronza, Mariana G. ;

Collares, Tiago ;

Buss, Julieti ;

Seixas, Fabiana K. ;

Alves, Diego ;

Lenardao, Eder J. .

ULTRASONICS SONOCHEMISTRY, 2017, 39 :827-836

[42] Effect of the extracellular component of bone marrow mesenchymal stromal cells from healthy donors on hematologic neoplasms and their angiogenesis [J].

Nina Gladkova ;

Tomohiro Umezu ;

Satoshi Imanishi ;

Chiaki Kawana ;

Junko H. Ohyashiki ;

Kazuma Ohyashiki .

Human Cell, 2020, 33 :599-609

[43] Effect of the extracellular component of bone marrow mesenchymal stromal cells from healthy donors on hematologic neoplasms and their angiogenesis [J].

Gladkova, Nina ;

Umezu, Tomohiro ;

Imanishi, Satoshi ;

Kawana, Chiaki ;

Ohyashiki, Junko H. ;

Ohyashiki, Kazuma .

HUMAN CELL, 2020, 33 (03) :599-609

[44] A multifunctional anti-AD approach: Design, synthesis, X-ray crystal structure, biological evaluation and molecular docking of chrysin derivatives [J].

Yang, Aihong ;

Liu, Chang ;

Zhang, Hongwei ;

Wu, Jianhua ;

Shen, Rui ;

Kou, Xiaodi .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 233

[45] Ultrasonic-assisted synthesis of chrysin derivatives linked with 1,2,3-triazoles by 1,3-dipolar cycloaddition reaction [J].

Jiang, Yuqin ;

Chen, Xiaolan ;

Qu, Lingbo ;

Wang, Junliang ;

Yuan, Jinwei ;

Chen, Senshen ;

Li, Xu ;

Qu, Chen .

ULTRASONICS SONOCHEMISTRY, 2011, 18 (02) :527-533

[46] Synthesis and biological evaluation of new 2-methoxyestradiol derivatives: Potent inhibitors of angiogenesis and tubulin polymerization [J].

Sun, Moran ;

Zhang, Yixin ;

Qin, Jinling ;

Ba, Mengyu ;

Yao, Yongfang ;

Duan, Yongtao ;

Liu, Hongmin ;

Yu, Dequan .

BIOORGANIC CHEMISTRY, 2021, 113

[47] Design, Synthesis and Biological Evaluation of Diosgenin-Amino Acid Derivatives with Dual Functions of Neuroprotection and Angiogenesis [J].

Cai, Desheng ;

Qi, Jinchai ;

Yang, Yuqin ;

Zhang, Wenxi ;

Zhou, Fei ;

Jia, Xiaohui ;

Guo, Wenbo ;

Huang, Xuemei ;

Gao, Feng ;

Chen, Hongshan ;

Li, Tong ;

Li, Guoping ;

Wang, Penglong ;

Zhang, Yuzhong ;

Lei, Haimin .

MOLECULES, 2019, 24 (22)

[48] Design and Synthesis of Novel Thiazolo[5,4-d]pyrimidine Derivatives as Potential Angiogenesis Inhibitors [J].

Xue, Wen-Jun ;

Du, Jian-Yao ;

Deng, Ya-Hui ;

Yan, Zhong-Hui ;

Liu, Ji-Ping ;

Liu, Yu ;

Sun, Li-Ping .

CHEMISTRY & BIODIVERSITY, 2019, 16 (08)

[49] Protective effect of troxerutin and cerebroprotein hydrolysate injection on cerebral ischemia through inhibition of oxidative stress and promotion of angiogenesis in rats [J].

Ma, Wenbing ;

Wang, Shixiang ;

Liu, Xuanlin ;

Tang, Fengru ;

Zhao, Peipei ;

Cheng, Kai ;

Zheng, Qiaowei ;

Zhuo, Yingchen ;

Zhao, Xue ;

Li, Xueqian ;

Feng, Weiyi .

MOLECULAR MEDICINE REPORTS, 2019, 19 (04) :3148-3158

[50] Design, synthesis, bioactivity, X-ray crystallography, and molecular docking studies of chrysin-1,3,5-triazine derivatives as anticancer agents [J].

Xue, Xuan-Yi ;

He, Jing-Liang ;

Song, Meng-Wei ;

Yu, Zi-en ;

Shuang-Liu ;

Lin, Meng-Jie ;

Zhang, Chi-Peng ;

Bo-Ding ;

Hao-Wang ;

Ma, Zhi-Hao ;

Zhang, Wei-Heng ;

Zou, Yang-Yang ;

Qing-Yuan ;

Jing-Ji ;

Shi, Da-Hua .

BIOORGANIC CHEMISTRY, 2025, 161

← 1 2 3 4 5 →