Synthetic studies on CP-225,917 and CP-263,114: concise synthesis of the bicyclic core using an intramolecular Mukaiyama aldol reaction

被引：19

作者：

Armstrong, A ^{[3
]}

Critchley, TJ

Gourdel-Martin, ME

Kelsey, RD

Mortlock, AA

机构：

[1] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

[2] AstraZeneca Pharmaceut, Macclesfield SK10 4TG, Cheshire, England

[3] Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2002年 / 11期

关键词：

D O I：

10.1039/b202752f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A concise synthesis of the bicyclo[4.3.1]dec-1(9)-en-10-one core of the natural products CP-225,917 and CP-263,114 is reported, employing an intramolecular Mukaiyama aldol cyclisation as a key step.

引用

页码：1344 / 1350

页数：7

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