Ultrafast vibrational dynamics of hydrogen bonds in the condensed phase

This review demonstrates the potential of nonlinear vibrational spectroscopy for reaching a microscopic understanding of hydrogen bonds in liquids. This field is of substantial current interest, with new developments in ultrafast technology and spectroscopy, e.g., toward multidimensional methods, and an extension of research to complex hydrogen-bonded systems going on. The extension of such studies from liquids to biologically relevant systems such as hydrogen bonds in proteins represents an important direction of research which will help to unravel the structure-function relationships of biomolecules.