Myriads: P-value-based multiple testing correction

被引：34

作者：

Carvajal-Rodriguez, Antonio ^{[1
]}

机构：

[1] Univ Vigo, Dept Biochem Genet & Immunol, Address Fac Biol, Vigo, Spain

来源：

BIOINFORMATICS | 2018年 / 34卷 / 06期

关键词：

TRUE NULL HYPOTHESES; FALSE DISCOVERY RATE; NUMBER;

D O I：

10.1093/bioinformatics/btx746

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Motivation: There are many multiple testing correction methods. Some of them are robust to various dependencies in the data while others are not. Some of the implementations have problems for managing high dimensional list of P-values as currently demanded by microarray and other omic technologies. Results: The program Myriads, formerly SGoF+, provides some of the most important P-value-based correction methods jointly with a test of dependency and a P-value simulator. Myriads easily manage hundreds of thousands of P-values.

引用

页码：1043 / 1045

页数：3

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