The OGTT is highly reproducible in Africans for the diagnosis of diabetes: Implications for treatment and protocol design

被引：12

作者：

Jagannathan, Ram ^{[1
]}

DuBose, Christopher W. ^{[2
]}

Mabundo, Lilian S. ^{[2
]}

Chung, Stephanie T. ^{[2
]}

Ha, Joon ^{[3
]}

Sherman, Arthur ^{[3
]}

Bergman, Michael ^{[4
]}

Sumner, Anne E. ^{[2
,5
]}

机构：

[1] Emory Univ, Sch Med, Dept Med, Atlanta, GA USA

[2] NIDDK, Sect Ethn & Hlth Diabet Endocrinol & Obes Branch, Bethesda, MD 20892 USA

[3] NIH, NIDDK, Lab Biol Modeling, Bldg 10, Bethesda, MD 20892 USA

[4] NYU, Sch Med, Dept Med & Populat Hlth, Div Endocrinol & Metab, New York, NY USA

[5] NYU, Natl Inst Minor Hlth & Hlth Dispar, Bethesda, MD USA

来源：

DIABETES RESEARCH AND CLINICAL PRACTICE | 2020年 / 170卷

关键词：

Diabetes; Africans; OGTT; Fasting plasma glucose; IMPAIRED FASTING GLUCOSE; TOLERANCE; POPULATION;

D O I：

10.1016/j.diabres.2020.108523

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Whether an OGTT reproducibly detects either type 2 diabetes (T2D) or prediabetes in Africans in unknown. Therefore, 131 Africans had two OGTT. Diagnostic reproducibility for T2D was excellent (kappa = 0.84), but only moderate for prediabetes (kappa = 0.51). A single OGTT positive for T2D may be sufficient to guide clinical care and inform epidemiologic study design. (C) 2020 Elsevier B.V. All rights reserved.

引用

页数：4

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