Joint Nutrition Society and Irish Nutrition and Dietetic Institute Symposium on 'Nutrition and autoimmune disease' Recent advances in genetic understanding of coeliac disease

被引：1
作者：
Feighery, Conleth F. [1 ]
McManus, Ross [2 ,3 ]
机构：
[1] Univ Dublin Trinity Coll, Dept Immunol, Dublin 8, Ireland
[2] St James Hosp, Inst Mol Med, Trinity Ctr Hlth Sci, Dublin 8, Ireland
[3] St James Hosp, Dept Clin Med, Trinity Ctr Hlth Sci, Dublin 8, Ireland
来源：
PROCEEDINGS OF THE NUTRITION SOCIETY | 2009年 / 68卷 / 02期
基金：
英国惠康基金;
关键词：
Coeliac disease; Genetic markers; Inflammatory pathways; TISSUE TRANSGLUTAMINASE; ADAPTER PROTEIN; HIGH PREVALENCE; RISK VARIANTS; LNK; CTLA4; IDENTIFICATION; ASSOCIATION; EXPRESSION; ANTIBODIES;
D O I：
10.1017/S0029665109001074
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Over the past 20 years major advances have been made in the diagnosis and understanding of pathogenic mechanisms relating to coeliac disease. Recently-identified genetic markers support the immunological-inflammatory nature of the disease. It is hoped that these newly-identified genes will assist further dissection of the inflammatory pathways in coeliac disease and give insight into why certain individuals develop intolerance to dietary gluten.
引用
收藏
页码：122 / 126
页数：5
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