Green synthesis and molecular recognition ability of patuletin coated gold nanoparticles

被引：45

作者：

Ateeq, Muhammad ^{[1
]}

Shah, Muhammad Raza ^{[1
]}

ul Ain, Noor ^{[1
,2
]}

Bano, Samina ^{[1
]}

Anis, Itrat ^{[2
]}

Lubna ^{[1
]}

Faizi, Shaheen ^{[1
]}

Bertino, Massimo F. ^{[3
]}

Naz, Syeda Sohaila ^{[4
]}

机构：

[1] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem & Biol Sci, Karachi 75270, Pakistan

[2] Univ Karachi, Dept Chem, Karachi 75270, Pakistan

[3] Virginia Commonwealth Univ, Dept Phys, Richmond, VA 23234 USA

[4] Natl Ctr Phys, NanoSci & Catalysis Div, Islamabad, Pakistan

来源：

BIOSENSORS & BIOELECTRONICS | 2015年 / 63卷

关键词：

Patuletin; Patuletin coated gold nanoparticles; Piroxicam; SPECTROPHOTOMETRIC DETERMINATION; HUMAN PLASMA; PIROXICAM; AU; ANTIBACTERIAL; CYCLODEXTRIN; FLUORESCENCE; TENOXICAM;

D O I：

10.1016/j.bios.2014.07.076

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Patuletin isolated from Tagetes patula was used as a capping and reducing agent to synthesize in one pot gold nanoparticles capped with patuletin. Conjugation of gold with patuletin was confirmed by FT-IR and UV-visible spectroscopy and amount of patuletin conjugated to gold nanoparticles was found to be 63.2% by weight. Particle sizes were measured by atomic force microscopy (AFM) and were found to have a mean diameter of about 45 nm. Patuletin-coated gold nanoparticles were found to be highly fluorescent. To examine their potential as chemical sensors, they were contacted with fourteen different drugs. Of these drugs, only one, piroxicam, was found to quench luminescence. Quenching obeyed Beer's law in a concentration range of 20-260 mu M. Important for molecular recognition applications, fluorescence quenching by piroxicam was not affected by pH variation, elevated temperatures, addition of other drugs and addition of blood plasma to the colloidal suspensions. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：499 / 505

页数：7

共 38 条

[1] RETRACTED: Synthesis and characterization of chitosan and grape polyphenols stabilized palladium nanoparticles and their antibacterial activity (Retracted article. See vol. 111, pg. 769, 2013) [J].