Buprenorphine and Methadone Maintenance Treatment - Sexual Behaviour and Dysfunction Prevalence

被引：10

作者：

Giacomuzzi, S. M. ^{[1
]}

Khreis, A.

Riemer, Y. ^{[1
]}

Garber, K. ^{[2
]}

Ertl, M. ^{[1
]}

机构：

[1] Med Univ Innsbruck, Univ Dept Psychiat & Psychotherapy, Univ Clin Psychiat & Social Psychiat, Innsbruck Gen Hosp, A-6020 Innsbruck, Austria

[2] Free Univ Bozen, Bolzano, Italy

来源：

LETTERS IN DRUG DESIGN & DISCOVERY | 2009年 / 6卷 / 01期

关键词：

Substituion; Methadone; Buprenorphine; Sexuality; Dysfunction prevalence;

D O I：

10.2174/157018009787158580

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Buprenorphine maintenance treatment has become a major intervention in the care and treatment of drug dependence in Europe. Still little is known about sexual behaviour and sexual dysfunction especially under buprenorphine or methadone maintenance treatment. Our study aimed to evaluate patterns of sexual behaviour and dysfunction prevalence within buprenorphine and methadone maintenance treatment. Significant differences between both groups could be observed regarding sexual excitation disturbances and ability to orgasm. 33.3% of the methadone-maintained group showed significantly higher sexual excitation disturbances (p = 0.006). Future studies of sexual dysfunction in opioid-treated persons should examine the potential benefits of dose reduction, androgen replacement, and choice of opioid.

引用

页码：13 / 13

页数：1

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