Diagnosis and classification of Addison's disease (autoimmune adrenalitis)

被引：38

作者：

Brandao Neto, Rodrigo Antonio ^{[1
]}

de Carvalho, Jozelio Freire ^{[2
]}

机构：

[1] Univ Sao Paulo, Fac Med, Hosp Clin, Emergency Div, Sao Paulo, Brazil

[2] Alianca Med Ctr, Div Rheumatol, Salvador, BA, Brazil

来源：

AUTOIMMUNITY REVIEWS | 2014年 / 13卷 / 4-5期

关键词：

STEROID 21-HYDROXYLASE AUTOANTIBODIES; REPLACEMENT THERAPY; MASS-SPECTROMETRY; ADULT PATIENTS; INSUFFICIENCY; PREVALENCE; ANTIBODIES; PROGRESSION; RESPONSES; RECOVERY;

D O I：

10.1016/j.autrev.2014.01.025

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Autoimmune adrenalitis, or autoimmune Addison disease (AAD), is the most prevalent cause of primary adrenal insufficiency in the developed world. MD is rare and can easily be misdiagnosed as other conditions. The diagnosis depends on demonstrating inappropriately low cortisol production and the presence of high titers of adrenal cortex autoantibodies (ACAs), along with excluding other causes of adrenal failure using other tests as necessary. The treatment corticosteroid replacement, and the prognosis following the treatment is the same as the normal population. Spontaneous recovery of adrenal function has been described but is rare. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：408 / 411

页数：4