A Case of Psoriasis Complicated by Breast Cancer after Systemic Treatments Including Biologics

被引：0

作者：

Morizane, Shin ^{[1
]}

Sugimoto, Saeko ^{[1
]}

Motoki, Takayuki ^{[2
]}

Katayama, Norihisa ^{[3
]}

Omori, Masako ^{[4
]}

Iwatsuki, Keiji ^{[1
]}

机构：

[1] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Dermatol, Okayama 7008558, Japan

[2] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Breast & Endocrinol Surg, Okayama 7008558, Japan

[3] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Radiol, Okayama 7008558, Japan

[4] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol, Okayama 7008558, Japan

来源：

ACTA MEDICA OKAYAMA | 2018年 / 72卷 / 02期

关键词：

psoriasis; systemic therapy; biologics; malignancy; POPULATION-BASED COHORT; RISK; CYCLOSPORINE; DISEASE;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Psoriasis is a common chronic inflammatory skin disorder that is characterized by scaly, erythematous, sharply demarcated plaques. The treatment for psoriasis has dramatically changed over the last 10 years with the introduction of biologics. However, the risk of cancer induced by biologics for psoriasis has not been fully analyzed, since these agents have such a short history of use. Here we report the case of a 74-year-old woman with psoriasis vulgaris and psoriatic arthritis complicated by breast cancer after systemic treatments including etretinate, cyclosporine, methotrexate, adalimumab, and ustekinumab.

引用

页码：185 / 187

页数：3

共 18 条

[11] The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses [J].

Lowes, Michelle A. ;

Russell, Chris B. ;

Martin, David A. ;

Towne, Jennifer E. ;

Krueger, James G. .

TRENDS IN IMMUNOLOGY, 2013, 34 (04) :174-181

[12] Guidelines of care for the management of psoriasis and psoriatic arthritis Section 4. Guidelines of care for the management and treatment of psoriasis with traditional systemic agents [J].

Menter, Alan ;

Korman, Neil J. ;

Elmets, Craig A. ;

Feldman, Steven R. ;

Gelfand, Joel M. ;

Gordon, Kenneth B. ;

Gottlieb, Alice B. ;

Koo, John Y. M. ;

Lebwohl, Mark ;

Lim, Henry W. ;

Van Voorhees, Abby S. ;

Beutner, Karl R. ;

Bhushan, Reva .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2009, 61 (03) :451-485

[13] Mechanisms of Disease: Psoriasis. [J].

Nestle, Frank O. ;

Kaplan, Daniel H. ;

Barker, Jonathan .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (05) :496-509

[14] Long-term safety of ustekinumab in patients with moderate-to-severe psoriasis: final results from 5 years of follow-up [J].

Papp, K. A. ;

Griffiths, C. E. M. ;

Gordon, K. ;

Lebwohl, M. ;

Szapary, P. O. ;

Wasfi, Y. ;

Chan, D. ;

Hsu, M. -C. ;

Ho, V. ;

Ghislain, P. D. ;

Strober, B. ;

Reich, K. .

BRITISH JOURNAL OF DERMATOLOGY, 2013, 168 (04) :844-854

[15] Risk of malignancies in psoriasis patients treated with cyclosporine: a 5 y cohort study [J].

Paul, CF ;

Ho, VC ;

McGeown, C ;

Christophers, E ;

Schmidtmann, B ;

Guillaume, JC ;

Lamarque, V ;

Dubertret, L .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2003, 120 (02) :211-216

[16] Malignant melanoma in patients treated for psoriasis with methoxsalen (psoralen) and ultraviolet A radiation (PUVA) [J].

Stern, RS ;

Nichols, KT ;

Vakeva, LH .

NEW ENGLAND JOURNAL OF MEDICINE, 1997, 336 (15) :1041-1045

[17] CARDIOVASCULAR-DISEASE, CANCER, AND CAUSE OF DEATH IN PATIENTS WITH PSORIASIS - 10 YEARS PROSPECTIVE EXPERIENCE IN A COHORT OF 1,380 PATIENTS [J].

STERN, RS ;

LANGE, R .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1988, 91 (03) :197-201

[18]

Stoica Loredana Elena, 2014, Curr Health Sci J, V40, P62, DOI 10.12865/CHSJ.40.01.12

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