Smart nanomaterials responsive to multiple chemical stimuli with controllable cooperativity

被引:139
作者
Liu, Juewen [1 ]
Lu, Yi [1 ]
机构
[1] Univ Illinois, Beckman Inst Adv Sci & Technol, Dept Chem, Urbana, IL 61801 USA
关键词
D O I
10.1002/adma.200600525
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Aptamer-linked smart materials responsive to a combination of any two analytes, including adenosine, cocaine, and K+, are demonstrated. The effect of small molecules on the properties of the nanomaterials can be either highly cooperative or non-cooperative, which can be described as logic gates with chemical inputs and colorimetric output (see figure).
引用
收藏
页码:1667 / 1671
页数:5
相关论文
共 33 条
  • [1] Programmable ligand-controlled riboregulators of eukaryotic gene expression
    Bayer, TS
    Smolke, CD
    [J]. NATURE BIOTECHNOLOGY, 2005, 23 (03) : 337 - 343
  • [2] Engineered allosteric ribozymes as biosensor components
    Breaker, RR
    [J]. CURRENT OPINION IN BIOTECHNOLOGY, 2002, 13 (01) : 31 - 39
  • [3] Temperature-programmed assembly of DNA:Au nanoparticle bioconjugates
    Dillenback, LM
    Goodrich, GP
    Keating, CD
    [J]. NANO LETTERS, 2006, 6 (01) : 16 - 23
  • [4] INVITRO SELECTION OF RNA MOLECULES THAT BIND SPECIFIC LIGANDS
    ELLINGTON, AD
    SZOSTAK, JW
    [J]. NATURE, 1990, 346 (6287) : 818 - 822
  • [5] Protein-dependent ribozymes report molecular interactions in real time
    Hartig, JS
    Najafi-Shoushtari, SH
    Grüne, I
    Yan, A
    Ellington, AD
    Famulok, M
    [J]. NATURE BIOTECHNOLOGY, 2002, 20 (07) : 717 - 722
  • [6] Aptamer-modified gold nanoparticles for colorimetric determination of platelet-derived growth factors and their receptors
    Huang, CC
    Huang, YF
    Cao, ZH
    Tan, WH
    Chang, HT
    [J]. ANALYTICAL CHEMISTRY, 2005, 77 (17) : 5735 - 5741
  • [7] A DNA APTAMER THAT BINDS ADENOSINE AND ATP
    HUIZENGA, DE
    SZOSTAK, JW
    [J]. BIOCHEMISTRY, 1995, 34 (02) : 656 - 665
  • [8] Jayasena SD, 1999, CLIN CHEM, V45, P1628
  • [9] Cooperative binding of effecters by an allosteric ribozyme
    Jose, AM
    Soukup, GA
    Breaker, RR
    [J]. NUCLEIC ACIDS RESEARCH, 2001, 29 (07) : 1631 - 1637
  • [10] Integrated nanoparticle-biomolecule hybrid systems: Synthesis, properties, and applications
    Katz, E
    Willner, I
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (45) : 6042 - 6108