5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazol-1-yl)phenyl)pyrimidine-2,4-diamine (WY-135), a novel ALK inhibitor, induces cell cycle arrest and apoptosis through inhibiting ALK and its downstream pathways in Karpas299 and H2228 cells (vol 284, pg 24, 2018)

被引：1
|
作者：
Han, Mengting [1 ]
Shen, Jiwei [1 ]
Wang, Lijing [1 ]
Wang, Yu [2 ]
Zhai, Xin [2 ]
Li, Yao [1 ]
Liu, Meiqiao [1 ]
Gao, Meiqi [1 ]
Li, Zengqiang [1 ]
Zuo, Daiying [1 ]
Wu, Yingliang [1 ]
机构：
[1] Shenyang Pharmaceut Univ, Dept Pharmacol, 103 Wenhua Rd, Shenyang 110016, Peoples R China
[2] Shenyang Pharmaceut Univ, Key Lab Struct Based Drug Design & Discovery, Minist Educ, 103 Wenhua Rd, Shenyang 110016, Peoples R China
来源：
CHEMICO-BIOLOGICAL INTERACTIONS | 2022年 / 356卷
关键词：
D O I：
10.1016/j.cbi.2022.109871
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页数：1
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