Microstructure, mechanical properties, in vitro degradation behavior and hemocompatibility of novel Zn-Mg-Sr alloys as biodegradable metals

被引：145

作者：

Liu, Xiwei ^{[1
,2
,3
]}

Sun, Jianke ^{[1
,2
,3
]}

Yang, Yinghong ^{[2
]}

Zhou, Feiyu ^{[2
]}

Pu, Zhongjie ^{[2
,3
]}

Li, Li ^{[1
]}

Zheng, Yufeng ^{[1
,4
]}

机构：

[1] Harbin Engn Univ, Ctr Biomed Mat & Engn, Harbin 150001, Peoples R China

[2] Lepu Med Technol Co Ltd, Beijing 102200, Peoples R China

[3] Natl Engn Res Ctr Heart Dis Explants Intervent Me, Beijing 102200, Peoples R China

[4] Peking Univ, Coll Engn, Dept Mat Sci & Engn, Beijing 100871, Peoples R China

来源：

MATERIALS LETTERS | 2016年 / 162卷

关键词：

Zn-Mg-Sr alloys; Biomaterials; Microstructure; Degradation behavior; Hemocompatibility; CORROSION PROPERTIES; MAGNESIUM ALLOYS;

D O I：

10.1016/j.matlet.2015.07.151

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The microstructure, mechanical properties, in vitro degradation behavior and hemocompatibility of novel Zn-1Mg-0.1Sr and Zn-1Mg-0.5Sr (wt%) ternary alloys were evaluated with pure Zn as control. The results indicated that Zn-Mg-Sr alloys exhibited much higher yield strength (YS), ultimate tensile strength (UTS), hardness and corrosion rate than those of pure Zn. But their elongation and hemolysis rates were reduced. Furthermore, the hot-rolled Zn-1Mg-0.1Sr alloy presented the superior mechanics performance (196.84 +/- 13.20 MPa, 300.08 +/- 6.09 MPa, 22.49 +/- 2.52%, 104.31 +/- 10.18 for YS, UTS, Elongation and hardness, respectively), appropriate corrosion rate (0.15 +/- 0.05 mm/year) and excellent hemocompatibility (hematolysis rate of 1.10 +/- 0.2% and no signs of thrombogenicity), showing a preferable candidate as the biodegradable implant material. (C) 2015 Published by Elsevier B.V.

引用

页码：242 / 245

页数：4

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