Chemical and biological evaluation of phyllanthus amarus as antiviral agent

被引：0

作者：

Abou Baker, Doha H. ^{[1
]}

El Senousy, Waleed M. ^{[2
]}

El Gengaihi, Souad ^{[1
]}

机构：

[1] Natl Res Ctr, Pharmaceut & Drug Ind Div, Med & Aromat Plants Dept, Cairo, Egypt

[2] Natl Res Ctr, Environm Res Div, Water Pollut Res Dept, Virol Lab, Cairo, Egypt

来源：

BIOSCIENCE RESEARCH | 2019年 / 16卷 / 01期

关键词：

Phyllanthus amarus; antiviral; lignans; isolation; identification; LIGNANS;

D O I：

暂无

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Phyllanthus amarus (Schum and Thonn) family Euphorbaceae, is a medicinal herb used extensively in many countries for variant medical purposes. The objective of the present study was to investigate the antiviral activity of the extracts as well as isolation and identification of the bioactive compounds. Promising HCV reduction was recorded with nontoxic dose of ethyl acetate extract (5.8 mu g/ml). Two lignans were isolated and identified by spectral tools; phyllanthin and hypophyllanthin, in addition to lignan lactone patavin.

引用

页码：522 / 528

页数：7

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