Microdosimetry for Pulsed E Fields in a Realistic Models of Cells and Endoplasmic Reticulum

被引：0
|
作者：
Denzi, Agnese [1 ]
Hanna, Hanna [2 ]
Andre, Franck M. [2 ]
Mir, Lluis M. [2 ]
Apollonio, Francesca [3 ]
Liberti, Micaela [3 ]
机构：
[1] Ist Italiano Tecnol, Ctr Life Nano Sci, Rome, Italy
[2] Univ Paris Saclay, Univ Paris Sud, CNRS, Gustave Roussy,Vectorol & Antitumor Therapies,UMR, Villejuif, France
[3] Univ Roma La Sapienza, ICEmB Dept Informat Engn Elect & Telecommun, Rome, Italy
来源：
2017 14TH INTERNATIONAL CONFERENCE ON SYNTHESIS, MODELING, ANALYSIS AND SIMULATION METHODS AND APPLICATIONS TO CIRCUIT DESIGN (SMACD) | 2017年
关键词：
microsecond pulsed electric field; endoplamic reticulum; electroporation; electropermeabilization; electropulsation; mesenchymal stem cells; MICROSECOND;
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
Microsecond pulsed electric fields (mu sPEFs) with amplitude of tens of kV/ m are used to permeabilize the plasma membrane whereas nanosecond pulsed electric fields of MV/m also permeabilize cell internal structures, such as the endoplasmic reticulum. In this work, a numerical realistic model of cell and its reticulum has been realized to study the use of mu sPEFs also for the permeabilization of this internal structure.
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页数：3
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