One-pot synthetic procedure for 2,2′-disubstituted biaryls via the Suzuki coupling reaction of aryl triflates in a biphasic solvent system

被引：13

作者：

Miura, Masanori ^{[1
]}

Koike, Takanori ^{[1
]}

Ishihara, Tsukasa ^{[1
]}

Hirayama, Fukushi ^{[1
]}

Sakamoto, Shuichi ^{[1
]}

Okada, Minoru ^{[1
]}

Ohta, Mitsuaki ^{[1
]}

Tsukamoto, Shin-ichi ^{[1
]}

机构：

[1] Astellas Pharma Inc, Inst Drug Discovery Res, Tsukuba, Ibaraki 3058585, Japan

来源：

SYNTHETIC COMMUNICATIONS | 2006年 / 36卷 / 24期

关键词：

biphasic solvent; 2,2 '-disubstituted biaryls; one-pot reaction; Suzuki coupling reaction; tetra(alkoxo)diboron;

D O I：

10.1080/00397910600948088

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot synthetic procedure for 2,2'-disubstituted biaryls was developed via a Suzuki cross-coupling reaction of aryl triflates in a biphasic solvent system. The effects of various bases and solvents were investigated. Results showed that the Na2CO3 - toluene/H2O combination gave the highest yields.

引用

页码：3809 / 3820

页数：12

共 35 条

[31] Ionic Liquid [bmim]BF4 as an Efficient and Recyclable Reaction Medium for the Synthesis of O-Acetyl Cyanohydrin via One-Pot Condensation of Aldehyde, TMSCN, and Ac2O
Shen, Zhi-Liang
Ji, Shun-Jun
SYNTHETIC COMMUNICATIONS, 2009, 39 (05) : 808 - 818
[32] One-pot Synthesis of Highly Functionalizable 3-(Phenylsulfonyl)-2,3-dihydro-4(1H)-quinolinones via a Cu-catalyzed Aza-Michael Addition/Cyclization Reaction
Kang, Seongil
Yoon, Hongju
Lee, Yunmi
CHEMISTRY LETTERS, 2016, 45 (12) : 1356 - 1358
[33] Synthesis of new 2-amino-4H-thiopyran derivatives via the one-pot reaction between 3,4-dihydro-3-((benzylamino)methylene)-4-thioxochromen-2-ones and alkyl-2-cyanoacetates in the presence of nano-ZnO catalysis
Aghaalizadeh, Tooran
Nasiri, Farough
Sabahi-Agabager, Leila
JOURNAL OF SULFUR CHEMISTRY, 2019, 40 (01) : 42 - 51
[34] Efficient on-water synthesis of novel pyrano[3,2-e][1,2,4]triazolo[1,5-a] pyrimidines via catalyst-free one-pot three-component reaction
Dastjerdi, Fatemeh Hamidi
Esmaeili, Abbas Ali
TETRAHEDRON, 2025, 176
[35] Synthesis of tetrahydropyrimidin-2-ones via FeCl3\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\hbox {FeCl}_{3}$$\end{document} catalyzed one-pot domino reaction of amines, methyl propiolate, aromatic aldehydes, and urea
Li-Li Zhang
Jing Sun
Chao-Guo Yan
Molecular Diversity, 2014, 18 (1) : 79 - 89

← 1 2 3 4 →