Tetrabutylammonium cyanide catalyzed diasteroselective cyanosliylation of chiral α-hydroxyketones

被引：40

作者：

Amurrio, I ^{[1
]}

Córdoba, R ^{[1
]}

Csákÿ, AG ^{[1
]}

Plumet, J ^{[1
]}

机构：

[1] Univ Complutense, Fac Quim, Dept Quim Organ, Madrid 28040, Spain

来源：

TETRAHEDRON | 2004年 / 60卷 / 46期

关键词：

tetrabutylammonium cyanide; alpha-hydroxyketones; alpha; beta-dihydroxynitriles;

D O I：

10.1016/j.tet.2004.07.101

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Tetrabutylammonium cyanide has been used as non-metallic catalyst for the diastereoselective cyanosilylation of alpha-hydroxyketones derived from the chiral pool. This affords alpha-substituted-alpha,beta-dihydroxynitriles with high levels of asymmetric induction. (C) 2004 Published by Elsevier Ltd.

引用

页码：10521 / 10524

页数：4

共 25 条

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