Management of Pouchitis and Other Common Complications of the Pouch

被引：59

作者：

Dalal, Robin L. ^{[1
]}

Shen, Bo ^{[2
]}

Schwartz, David A. ^{[1
]}

机构：

[1] Vanderbilt Univ, Med Ctr, Div Gastroenterol Hepatol & Nutr, Nashville, TN 37232 USA

[2] Cleveland Clin Fdn, Dept Gastroenterol Hepatol, 9500 Euclid Ave, Cleveland, OH 44195 USA

来源：

INFLAMMATORY BOWEL DISEASES | 2018年 / 24卷 / 05期

关键词：

Crohn's disease; ileal pouch-anal anastomosis; pouchitis; restorative proctocolectomy; treatment; ulcerative colitis; CHRONIC REFRACTORY POUCHITIS; INFLAMMATORY-BOWEL-DISEASE; PLACEBO-CONTROLLED TRIAL; FAMILIAL ADENOMATOUS POLYPOSIS; PRIMARY SCLEROSING CHOLANGITIS; LACTOBACILLUS-RHAMNOSUS GG; ILEAL-POUCH; ANAL-ANASTOMOSIS; ULCERATIVE-COLITIS; CROHNS-DISEASE;

D O I：

10.1093/ibd/izy020

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) has become the preferred surgical treatment for refractory or complicated ulcerative colitis (UC) and familial adenomatous polyposis (FAP). Pouchitis is the most common complication of this procedure and can occur in about 50% of patients. Treatment of pouchitis depends on the phenotype of disease. Pouchitis can be classified as acute, chronic/refractory, or secondary pouchitis, which includes pouchitis occurring due to Crohn's disease (CD). CD of the pouch is becoming an increasingly recognized problem, and management is challenging. This article reviews the literature and offers treatment recommendations regarding management of pouchitis and CD of the pouch.

引用

页码：989 / 996

页数：8

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