Intermittent and continuous energy restriction result in similar weight loss, weight loss maintenance, and body composition changes in a 6 month randomized pilot study

被引:23
作者
Steger, Felicia L. [1 ]
Donnelly, Joseph E. [2 ]
Hull, Holly R. [1 ]
Li, Xinyang [3 ]
Hu, Jinxiang [4 ]
Sullivan, Debra K. [1 ]
机构
[1] Univ Kansas, Med Ctr, Dept Dietet & Nutr, Kansas City, KS 66103 USA
[2] Univ Kansas, Med Ctr, Ctr Phys Act & Weight Management, Kansas City, KS 66103 USA
[3] Texas Tech Univ, Ctr Res Leadership & Educ, Lubbock, TX 79409 USA
[4] Univ Kansas, Dept Biostat & Data Sci, Med Ctr, Kansas City, KS 66103 USA
关键词
intermittent energy restriction; intermittent fasting; very-low calorie diet; weight management; body composition; calorie restriction; DISEASE RISK MARKERS; LOW-CALORIE DIET; ALTERNATE-DAY; PRACTICE GUIDELINES; AMERICAN-COLLEGE; TASK-FORCE; OVERWEIGHT; EXERCISE; PROGRAM; OBESITY;
D O I
10.1111/cob.12430
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Poor adherence is a barrier to successful weight control. Intermittent energy restriction (IER) provides an alternative approach to those for whom daily energy restriction is not ideal. This study assessed changes in weight, body composition, and macronutrient intake for an IER and a continuous energy restriction (CONT) approach within a multicomponent weight management intervention. We randomized 35 adults with overweight/obesity (BMI = 31.2 +/- 2.4 kg/m(2)) to CONT or IER for 24 weeks (12-week weight loss intervention and 12 weeks of weight loss maintenance). Diets were delivered within a multimodal weight management program including weekly group meetings with a registered dietitian, increased physical activity, and a comprehensive lifestyle change program. Retention and adherence were similar for CONT and IER. Weight, BMI, fat mass, percentage body fat, waist circumference, hip circumference, blood pressure, and heart rate all decreased after 24 weeks (all, P < .01), but there were no main effects of group (all, P > .27). Weight loss was clinically relevant in both CONT (11.38 +/- 7.9%) and IER (9.37 +/- 9.7%), and the proportion of each group achieving 5% weight loss was 82 and 61% (P = .16), respectively. Participant satisfaction was high in both groups. The results from this study (a) support the feasibility of IER as an alternative for weight loss and weight loss maintenance, (b) indicate that IER is an effective alternative to CONT for weight control and improvements in body composition, and (c) emphasize the importance of intensive lifestyle interventions with ongoing support for effective behaviour modification.
引用
收藏
页数:14
相关论文
共 48 条
  • [1] Alternate-day versus daily energy restriction diets: which is more effective for weight loss? A systematic review and meta-analysis
    Alhamdan, B. A.
    Garcia-Alvarez, A.
    Alzahrnai, A. H.
    Karanxha, J.
    Stretchberry, D. R.
    Contrera, K. J.
    Utria, A. F.
    Cheskin, L. J.
    [J]. OBESITY SCIENCE & PRACTICE, 2016, 2 (03): : 293 - 302
  • [2] Long-term weight maintenance after an intensive weight-loss program
    Anderson, JW
    Vichitbandra, S
    Qian, W
    Kryscio, RJ
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 1999, 18 (06) : 620 - 627
  • [3] [Anonymous], 2010, Dietary Guidelines for Americans, 2010
  • [4] [Anonymous], 2009, National Health and Nutrition Examination Survey
  • [5] Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting
    Anton, Stephen D.
    Moehl, Keelin
    Donahoo, William T.
    Marosi, Krisztina
    Lee, Stephanie A.
    Mainous, Arch G., III
    Leeuwenburgh, Christiaan
    Mattson, Mark P.
    [J]. OBESITY, 2018, 26 (02) : 254 - 268
  • [6] Antoni R, 2018, BRIT J NUTR, V119, P507, DOI [10.1017/S0007114517003890, 10.1017/s0007114517003890]
  • [7] Effectiveness of a Total Meal Replacement Program (OPTIFAST Program) on Weight Loss: Results from the OPTIWIN Study
    Ard, Jamy D.
    Lewis, Kristina H.
    Rothberg, Amy
    Auriemma, Anthony
    Coburn, Sally L.
    Cohen, Sarah S.
    Loper, Judy
    Matarese, Laura
    Pories, Walter J.
    Periman, Seletha
    [J]. OBESITY, 2019, 27 (01) : 22 - 29
  • [8] A systematic review and meta-analysis of the effectiveness of meal replacements for weight loss
    Astbury, Nerys M.
    Piernas, Carmen
    Hartmann-Boyce, Jamie
    Lapworth, Sophia
    Aveyard, Paul
    Jebb, Susan A.
    [J]. OBESITY REVIEWS, 2019, 20 (04) : 569 - 587
  • [9] Alternate Day Fasting and Endurance Exercise Combine to Reduce Body Weight and Favorably Alter Plasma Lipids in Obese Humans
    Bhutani, Surabhi
    Klempel, Monica C.
    Kroeger, Cynthia M.
    Trepanowski, John F.
    Varady, Krista A.
    [J]. OBESITY, 2013, 21 (07) : 1370 - 1379
  • [10] The Science of Obesity Management: An Endocrine Society Scientific Statement
    Bray, George A.
    Heisel, William E.
    Afshin, Ashkan
    Jensen, Michael D.
    Dietz, William H.
    Long, Michael
    Kushner, Robert F.
    Daniels, Stephen R.
    Wadden, Thomas A.
    Tsai, Adam G.
    Hu, Frank B.
    Jakicic, John M.
    Ryan, Donna H.
    Wolfe, Bruce M.
    Inge, Thomas H.
    [J]. ENDOCRINE REVIEWS, 2018, 39 (02) : 79 - 132