Transient Remission of Childhood Acute Lymphoblastic and Myeloid Leukemia Without Any Cytostatic Treatment: 2 Case Reports and a Review of Literature

被引：8

作者：

Pluchart, Claire ^{[1
,2
]}

Munzer, Martine ^{[1
,2
]}

Mauran, Pierre ^{[2
]}

Abely, Michel ^{[2
]}

机构：

[1] CHU Reims, Amer Mem Hosp, Serv Pediat A, Unite Oncol Pediat, F-51092 Reims, France

[2] CHU Reims, Amer Mem Hosp, Serv Pediat A, F-51092 Reims, France

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2015年 / 37卷 / 01期

关键词：

children; acute lymphoblastic leukemia; acute myeloid leukemia; spontaneous remission; transient remission; ACUTE MYELOGENOUS LEUKEMIA; ACUTE MONOCYTIC LEUKEMIA; TUMOR-NECROSIS-FACTOR; OF-THE-LITERATURE; INFECTION; ADULT; SEPSIS;

D O I：

10.1097/MPH.0000000000000152

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Transient remissions (TRs) of acute leukemia without any antileukemic treatment are extremely rare events. We report 2 TRs of acute lymphoblastic leukemia and acute myeloid leukemia in a 2-year-old boy and a 12-year-old girl, respectively, both associated with red blood cells and platelets transfusions and infection. These 2 factors are frequently present in previously reported cases and could induce a stimulation of the immune system although the underlying mechanisms of TRs are still unknown.

引用

页码：68 / 71

页数：4

共 21 条

[1] Spontaneous remission of acute monocytic leukemia after infection with Clostridium septicum [J].

Al-Tawfiq, J. A. ;

Al-Khatti, A. A. .

INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 2007, 29 (05) :386-389

[2] SPONTANEOUS REMISSION IN ACUTE LEUKEMIA - REPORT OF A CASE COMPLICATED BY ECLAMPSIA [J].

BIRGE, RF ;

JENKS, AL ;

DAVIS, SK .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1949, 140 (07) :589-592

[3] THE APLASTIC PRESENTATION OF CHILDHOOD LEUKEMIA - A FEATURE OF COMMON-ALL [J].

BREATNACH, F ;

CHESSELLS, JM ;

GREAVES, MF .

BRITISH JOURNAL OF HAEMATOLOGY, 1981, 49 (03) :387-393

[4] Discordance of MLL-rearranged (MLL-R) infant acute lymphoblastic leukemia in monozygotic twins with spontaneous clearance of preleukemic clone in unaffected twin [J].

Chuk, Meredith K. ;

McIntyre, Emily ;

Small, Donald ;

Brown, Patrick .

BLOOD, 2009, 113 (26) :6691-6694

[5] Hematologic and cytogenetic spontaneous remission in acute monocytic leukemia (FAB M5b) with trisomy 8 [J].

Daccache, Antoine ;

Kizhakekuttu, Tinoy ;

Siebert, James ;

Veeder, Michael .

JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (03) :344-346

[6] INCREASED SERUM TUMOR-NECROSIS-FACTOR DURING TRANSIENT REMISSION IN ACUTE-LEUKEMIA [J].

JIMEMEZ, C ;

RIBERA, JM ;

ABAD, E ;

PINTOS, G ;

MILLA, F ;

JUNCA, J ;

FELIU, E .

LANCET, 1993, 341 (8860) :1600-1600

[7] SPONTANEOUS REMISSION IN ACUTE MYELOGENOUS LEUKEMIA IN THE ADULT [J].

LACHANT, NA ;

GOLDBERG, J ;

NELSON, DA ;

GOTTLIEB, AJ .

AMERICAN JOURNAL OF MEDICINE, 1979, 67 (04) :687-692

[8] An unusual case of smoldering AML with prolonged indolent clinical course and spontaneous remission in the terminal phase [J].

Marisavljevic, Dragomir ;

Markovic, Olivera ;

Zivkovic, Radmila .

MEDICAL ONCOLOGY, 2009, 26 (04) :476-479

[9] A prospective study of the natural history of transient leukemia (TL) in neonates with Down syndrome (DS): Children's Oncology Group (COG) study POG-9481 [J].

Massey, Gita V. ;

Zipursky, Alvin ;

Chang, Myron N. ;

Doyle, John J. ;

Nasim, Suhail ;

Taub, Jeffrey W. ;

Ravindranath, Yaddanapudi ;

Dahl, Gary ;

Weinstein, Howard J. .

BLOOD, 2006, 107 (12) :4606-4613

[10]

Matsushita K, 1999, AM J HEMATOL, V61, P144, DOI 10.1002/(SICI)1096-8652(199906)61:2<144::AID-AJH13>3.0.CO

← 1 2 3 →