Hydrogels as Antibacterial Biomaterials

被引：41
作者：
Xu, Weiguo [1 ]
Dong, Shujun [1 ,4 ]
Han, Yuping [1 ,5 ]
Li, Shuqiang [1 ,2 ]
Liu, Yang [3 ]
机构：
[1] Chinese Acad Sci, Changchun Inst Appl Chem, Key Lab Polymer Ecomat, Changchun 130021, Jilin, Peoples R China
[2] Jilin Univ, Hosp 1, Dept Bone & Joint Surg, Changchun 130022, Jilin, Peoples R China
[3] Jilin Univ, Sch Life Sci, Changchun 130012, Jilin, Peoples R China
[4] Jilin Univ, Stomatol Hosp, VIP Integrated Dept, Changchun 130021, Jilin, Peoples R China
[5] Jilin Univ, China Japan Union Hosp, Dept Urol, Changchun 130033, Jilin, Peoples R China
来源：
CURRENT PHARMACEUTICAL DESIGN | 2018年 / 24卷 / 08期
基金：
中国国家自然科学基金;
关键词：
Polymer; hydrogel; antibiotic; antibacterial capability; biomedical application; tissue engineering; WOUND DRESSINGS; DELIVERY-SYSTEM; DRUG-RELEASE; THERMOSENSITIVE HYDROGEL; ANTIMICROBIAL PROPERTIES; IN-VITRO; CARBOXYMETHYL CHITOSAN; PHOTODYNAMIC THERAPY; RESISTANT BACTERIA; SENSITIVE HYDROGEL;
D O I：
10.2174/1381612824666180213122953
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Hydrogels, as a class of materials for tissue engineering and drug delivery, have high water content and solid-like mechanical properties. Currently, hydrogels with an antibacterial function are a research hotspot in biomedical field. Many advanced antibacterial hydrogels have been developed, each possessing unique qualities, namely high water swellability, high oxygen permeability, improved biocompatibility, ease of loading and releasing drugs and structural diversity. In this article, an overview is provided on the preparation and applications of various antibacterial hydrogels. Furthermore, the prospects in biomedical researches and clinical applications are predicted.
引用
收藏
页码：843 / 854
页数：12
相关论文
共 94 条
  • [1] [Anonymous], BMJ BRIT MED J
  • [2] Magnetically mediated release of ciprofloxacin from polyvinyl alcohol based superparamagnetic nanocomposites
    Bajpai, A. K.
    Gupta, Rashmi
    [J]. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2011, 22 (02) : 357 - 369
  • [3] Curcumin Nanoparticles: Preparation, Characterization, and Antimicrobial Study
    Bhawana
    Basniwal, Rupesh Kumar
    Buttar, Harpreet Singh
    Jain, V. K.
    Jain, Nidhi
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2011, 59 (05) : 2056 - 2061
  • [4] DNA as a target for antimicrobials
    Bolhuis, Albert
    Aldrich-Wright, Janice R.
    [J]. BIOORGANIC CHEMISTRY, 2014, 55 : 51 - 59
  • [5] Synthesis, characterization and in vitro antimicrobial activities of boron/starch/polyvinyl alcohol hydrogels
    Bursali, Elif Ant
    Coskun, Senem
    Kizil, Murat
    Yurdakoc, Muruvvet
    [J]. CARBOHYDRATE POLYMERS, 2011, 83 (03) : 1377 - 1383
  • [6] Cabral JD, 2016, SPR SER POLYM COMPOS, P153, DOI 10.1007/978-3-319-25322-0_6
  • [7] Covalently antibacterial alginate-chitosan hydrogel dressing integrated gelatin microspheres containing tetracycline hydrochloride for wound healing
    Chen, Huinan
    Xing, Xiaodong
    Tan, Huaping
    Jia, Yang
    Zhou, Tianle
    Chen, Yong
    Ling, Zhonghua
    Hu, Xiaohong
    [J]. MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2017, 70 : 287 - 295
  • [8] Design and in vitro evaluation of a novel poly(methacrylic acid)/metronidazole antibacterial nanogel as an oral dosage formZ
    Chen, Tao
    Chen, Liang
    Li, Haicheng
    Chen, Yuhui
    Guo, Huixin
    Shu, Yang
    Chen, Zhiyu
    Cai, Changhui
    Guo, Lina
    Zhang, Xianen
    Zhou, Lin
    Zhong, Qiu
    [J]. COLLOIDS AND SURFACES B-BIOINTERFACES, 2014, 118 : 65 - 71
  • [9] Dextrin and Poly(acrylic acid)-Based Biodegradable, Non-Cytotoxic, Chemically Cross-Linked Hydrogel for Sustained Release of Ornidazole and Ciprofloxacin
    Das, Dipankar
    Ghosh, Paulomi
    Dhara, Santanu
    Panda, Asit Baran
    Pal, Sagar
    [J]. ACS APPLIED MATERIALS & INTERFACES, 2015, 7 (08) : 4791 - 4803
  • [10] Dextrin cross linked with poly(HEMA): a novel hydrogel for colon specific delivery of ornidazole
    Das, Dipankar
    Das, Raghunath
    Ghosh, Paulomi
    Dhara, Santanu
    Panda, Asit Baran
    Pal, Sagar
    [J]. RSC ADVANCES, 2013, 3 (47) : 25340 - 25350
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