Noninvasive photothermal cancer therapy nanoplatforms via integrating nanomaterials and functional polymers

被引：160

作者：

Ban, Qingfu ^{[1
]}

Bai, Ting ^{[1
]}

Duan, Xiao ^{[1
]}

Kong, Jie ^{[1
]}

机构：

[1] Northwestern Polytech Univ, MOE Key Lab Space Appl Phys & Chem, Shaanxi Key Lab Macromol Sci & Technol, Sch Sci, Xian 710072, Peoples R China

来源：

BIOMATERIALS SCIENCE | 2017年 / 5卷 / 02期

基金：

中国国家自然科学基金;

关键词：

RAY COMPUTED-TOMOGRAPHY; COPPER SULFIDE NANOPARTICLES; MESOPOROUS SILICA NANOPARTICLES; PHOTOACOUSTIC CONTRAST AGENT; PRUSSIAN BLUE NANOPARTICLES; ENCAPSULATED GOLD NANORODS; AGONISTIC CD40 ANTIBODIES; ANTICANCER DRUG-DELIVERY; WALLED CARBON NANOTUBES; REDUCED GRAPHENE OXIDE;

D O I：

10.1039/c6bm00600k

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

In the cutting-edge field of cancer therapy, noninvasive photothermal therapy (PTT) has received great attention because it is considered to overcome the drawbacks of conventional surgery, radiotherapy and chemotherapy of severe body injuries and side effects on the immune system. The construction of PTT therapeutic and theranostic nanoplatforms is the key issue in achieving tumor targeting, imaging and therapy in a synergetic manner. In this review, we focus on the recent advances in constructing PTT therapeutic and theranostic nanoplatforms by integrating nanomaterials and functional polymers. The noninvasive photothermal cancer therapy mechanism and achievement strategies of PTT therapeutic and theranostic nanoplatforms are presented as well as the innovative construction strategies and perspectives for the future. Owing to their high tumor ablation efficiency, biological availability and low-or nontoxicity, PTT therapeutic and theranostic nanoplatforms are promising and emerging in medicine and clinical applications.

引用

页码：190 / 210

页数：21

共 235 条

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