Congenital diaphragmatic hernia: an overview of the etiology and current management

被引:34
作者
Gaxiola, Alejandra [1 ]
Varon, Joseph [2 ,3 ]
Valladolid, Genaro [1 ]
机构
[1] Univ Autonoma Baja California, Tijuana, Baja California, Mexico
[2] Univ Texas Houston, Hlth Sci Ctr, Houston, TX USA
[3] Univ Texas Houston, Med Branch Galveston, St Lukes Episcopal Hosp, Houston, TX USA
关键词
Bochdalek; Congenital diaphragmatic hernia; Diaphragm; Pulmonary hypoplasia; EXTRACORPOREAL MEMBRANE-OXYGENATION; TRACHEAL OCCLUSION; LUNG HYPOPLASIA; VITAMIN-A; PREOPERATIVE STABILIZATION; POSTNATAL MANAGEMENT; PULMONARY HYPOPLASIA; CHROMOSOME; 15Q26; NITROFEN MODEL; NITRIC-OXIDE;
D O I
10.1111/j.1651-2227.2008.01212.x
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Aim: To review provide an overview of the etiology and current strategies in the management of congenital diaphragmatic hernia (CDH). Methods: We did a comprehensive review of research trends, evidence based studies and epidemiologic studies. Results: CDH is a life-threatening pathology in infants, and a major cause of death due to the pulmonary hypoplasia and pulmonary hypertension. There is much research related to elucidating the etiology of CDH and developing management strategies to improve the outcomes in these infants. Conclusion: An early diagnosis with increased understanding of this disease is a crucial factor for a timely approach to managing the critically ill infant, and to offer the potential for improved outcomes and substantial reductions in morbidity.
引用
收藏
页码:621 / 627
页数:7
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