Moral assessment of growth hormone therapy for children with idiopathic short stature

被引:11
作者
Verweij, M [1 ]
Kortmann, F [1 ]
机构
[1] ACAD HOSP NIJMEGEN ST RADBOUD, NIJMEGEN, NETHERLANDS
关键词
ethics; medical; growth-disorders drug therapy; endocrinology; philosophy; growth hormone therapy; children with idiopathic short stature;
D O I
10.1136/jme.23.5.305
中图分类号
B82 [伦理学(道德学)];
学科分类号
摘要
The prescription of growth hormone therapy for children who are not growth hormone deficient is one of the controversies in contemporary paediatric endocrinology. Is it morally appropriate to enhance the growth, by means of medical treatment, of a child with idiopathic short stature? The medical, moral, and philosophical questions in this area are many. Data on the effects of human growth hormone (hGH) treatment will not on their own provide us with answers, as these effects have to be evaluated from a normative perspective. In this article we consider hGH treatment for children of idiopathic short stature from three normative perspectives: the goals of medicine, the good of the patient, and the public good. We argue that the prevention of psychological and social problems due to short stature (and not merely the enhancement of growth) should be the ultimate goal of medical treatment and research.
引用
收藏
页码:305 / 309
页数:5
相关论文
共 50 条
  • [21] Criteria for Treating Children with Idiopathic Short Stature: Laboratory (Biochemical)
    Chernausek, Steven D.
    HORMONE RESEARCH IN PAEDIATRICS, 2011, 76 : 18 - 20
  • [22] GH Resistance Is a Component of Idiopathic Short Stature: Implications for rhGH Therapy
    Savage, Martin O.
    Storr, Helen L.
    FRONTIERS IN ENDOCRINOLOGY, 2021, 12
  • [23] Beyond Growth Hormone Association of Short Stature Types and Growth Hormones With Scoliosis
    Hong, Haofeng
    Hu, Jiasheng
    Xu, Honghao
    Xia, Dongdong
    Pan, Xiangxiang
    Chen, Xibang
    Guo, Quanquan
    Zhang, Shuhao
    Chen, Jiaoxiang
    Wu, Yaosen
    Leng, Huijie
    Zhang, Xiaolei
    Wang, Xiangyang
    Huang, Chongan
    SPINE, 2024, 49 (04) : 221 - 231
  • [24] Deterioration of visual acuity associated with growth hormone therapy in a child with extreme short stature and high hypermetropia
    Paterson, Wendy F.
    Kelly, Brian
    Newman, William
    Savage, Martin O.
    Camacho-Hubner, Cecilia
    Dutton, Gordon N.
    Tolmie, John
    Donaldson, Malcolm D. C.
    HORMONE RESEARCH, 2007, 67 (02) : 67 - 72
  • [25] Growth hormone therapy and short stature-related distress: A randomized placebo-controlled trial
    Shemesh-Iron, Moran
    Lazar, Liora
    Lebenthal, Yael
    Nagelberg, Nessia
    Tenenbaum, Ariel
    Ezra, Revital
    Leffler, Nir
    Yackobovitch-Gavan, Michal
    Schoenberg-Taz, Michal
    Phillip, Moshe
    CLINICAL ENDOCRINOLOGY, 2019, 90 (05) : 690 - 701
  • [26] Late pubertal growth spurt in a girl with growth hormone deficiency: Is Kaufmann therapy effective in a girl with short stature who responds poorly to growth hormone therapy and estrogen-replacement therapy?
    Yasuda, Katsuhiko
    JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 2017, 43 (05) : 951 - 956
  • [27] Idiopathic Short Stature A Clinical Review
    Cohen, Laurie E.
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2014, 311 (17): : 1787 - 1796
  • [28] Growth hormone therapy for short children born small for gestational age
    Chatelain, P.
    Carrascosa, A.
    Bona, G.
    Ferrandez-Longas, A.
    Sippell, W.
    HORMONE RESEARCH, 2007, 68 (06) : 300 - 309
  • [29] Once-Weekly Administration of Sustained-Release Growth Hormone in Korean Prepubertal Children with Idiopathic Short Stature: A Randomized, Controlled Phase II Study
    Hwang, Jin Soon
    Lee, Hae Sang
    Lee, Kee-Hyoung
    Yoo, Han-Wook
    Lee, Dae-Yeol
    Suh, Byung-Kyu
    Ko, Cheol Woo
    Chung, Woo Yeong
    Jin, Dong-Kyu
    Shin, Choong Ho
    Han, Heon-Seok
    Han, Song
    Kim, Ho-Seong
    HORMONE RESEARCH IN PAEDIATRICS, 2018, 90 (01): : 54 - 63
  • [30] Psychological Functioning in Idiopathic Short Stature
    Noeker, Meinolf
    HORMONE RESEARCH IN PAEDIATRICS, 2011, 76 : 52 - 56