Moral assessment of growth hormone therapy for children with idiopathic short stature

被引:11
|
作者
Verweij, M [1 ]
Kortmann, F [1 ]
机构
[1] ACAD HOSP NIJMEGEN ST RADBOUD, NIJMEGEN, NETHERLANDS
关键词
ethics; medical; growth-disorders drug therapy; endocrinology; philosophy; growth hormone therapy; children with idiopathic short stature;
D O I
10.1136/jme.23.5.305
中图分类号
B82 [伦理学(道德学)];
学科分类号
摘要
The prescription of growth hormone therapy for children who are not growth hormone deficient is one of the controversies in contemporary paediatric endocrinology. Is it morally appropriate to enhance the growth, by means of medical treatment, of a child with idiopathic short stature? The medical, moral, and philosophical questions in this area are many. Data on the effects of human growth hormone (hGH) treatment will not on their own provide us with answers, as these effects have to be evaluated from a normative perspective. In this article we consider hGH treatment for children of idiopathic short stature from three normative perspectives: the goals of medicine, the good of the patient, and the public good. We argue that the prevention of psychological and social problems due to short stature (and not merely the enhancement of growth) should be the ultimate goal of medical treatment and research.
引用
收藏
页码:305 / 309
页数:5
相关论文
共 50 条
  • [1] Idiopathic short stature: Management and growth hormone treatment
    Wit, J. M.
    Reiter, E. O.
    Ross, J. L.
    Saenger, P. H.
    Savage, M. O.
    Rogol, A. D.
    Cohen, P.
    GROWTH HORMONE & IGF RESEARCH, 2008, 18 (02) : 111 - 135
  • [2] Growth hormone use in the treatment of idiopathic short stature
    Zucchini, Stefano
    CURRENT OPINION IN INVESTIGATIONAL DRUGS, 2008, 9 (04) : 396 - 401
  • [3] Initiation of growth hormone therapy in idiopathic short stature: do gender differences exist?
    Ben-Ari, Tal
    Lebenthal, Yael
    Phillip, Moshe
    Lazar, Liora
    JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, 2015, 28 (1-2): : 101 - 104
  • [4] Growth hormone therapy for short stature: Is the benefit worth the burden?
    Allen, David B.
    PEDIATRICS, 2006, 118 (01) : 343 - 348
  • [5] Efficacy and Safety of Human Growth Hormone in Idiopathic Short Stature
    Songxue Tao
    Guimei Li
    Qian Wang
    Yanyan Hu
    The Indian Journal of Pediatrics, 2015, 82 : 625 - 628
  • [6] Efficacy and Safety of Human Growth Hormone in Idiopathic Short Stature
    Tao, Songxue
    Li, Guimei
    wang, Qian
    Hu, Yanyan
    INDIAN JOURNAL OF PEDIATRICS, 2015, 82 (07): : 625 - 628
  • [7] The effect of growth hormone treatment on craniofacial growth in short stature children
    Chung, Sung-Ho
    Kim, Jin-Wook
    Park, Yong-Hoon
    Hwang, Chung-Ju
    Lee, Hee-Kyung
    KOREAN JOURNAL OF ORTHODONTICS, 2010, 40 (04): : 227 - 238
  • [8] Psychosocial adaptation to short stature - An indication for growth hormone therapy?
    Wygold, T
    HORMONE RESEARCH, 2002, 58 : 20 - 23
  • [9] Vitamin D, calcium and phosphorus status in children with short stature - effect of growth hormone therapy
    Klatka, Maria
    Partyka, Malgorzata
    Polak, Agnieszka
    Terpilowska, Barbara
    Terpilowski, Michal
    Chalas, Renata
    ANNALS OF AGRICULTURAL AND ENVIRONMENTAL MEDICINE, 2021, 28 (04) : 686 - 691
  • [10] Symptomatic versus substitution growth hormone therapy in short children: From auxology towards a comprehensive multidimensional assessment of short stature and related interventions
    Haverkamp, F
    Eiholzer, U
    Ranke, MB
    Noeker, M
    JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, 2000, 13 (04): : 403 - 408