Combined diffusion-weighted and spectroscopic MR imaging in Creutzfeldt-Jakob disease

被引：32
|
作者：
Lim, CCT [1 ]
Tan, K
Verma, KK
Yin, H
Venketasubramanian, N
机构：
[1] Natl Inst Neurosci, Dept Neuroradiol, Singapore, Singapore
[2] Natl Inst Neurosci, Dept Neurol, Singapore, Singapore
来源：
MAGNETIC RESONANCE IMAGING | 2004年 / 22卷 / 05期
关键词：
magnetic resonance imaging; nuclear magnetic resonance; spectroscopic imaging; echo-planar imaging; Creutzfeldt-Jakob syndrome;
D O I：
10.1016/j.mri.2004.01.042
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
A 49-year-old woman presented with progressive dementia. Diffusion-weighted MR images showed abnormalities in the cerebral cortex as well as the putamen and caudate head bilaterally. MR spectroscopic imaging revealed marked asymmetric decrease of normal metabolites in the right basal ganglia, with concordant hypoperfusion on single photon emission computed tomography. Diffusion-weighted MR imaging is more sensitive to cortical involvement in sporadic Creutzfeldt-Jakob Disease, and MR spectroscopy may yield evidence of asymmetric involvement. Combined functional and metabolic MR imaging may be useful in studying CJD. (C) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码：625 / 629
页数：5
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