Synthetic, spectroscopic, X-ray structural and antimicrobial studies of 1,3-dithia-2-stibacyclopentane derivatives of phosphorus based dithiolato ligands

Some mixed 1,3-dithia-2-stibacyclopentane derivatives with phosphorus based dithiolato ligands of the types (SCH2CH2SS) over bar bS (S) (POGO) over bar {where G = -CH(Me)-CH(Me)- and -C(Me)(2)-C(Me)(2)-} and (SCH2SS) over bar bS(S)P(OR)(2) {where R = Pr '', Bu '' and Ph} have been synthesized by the reaction of 2-chloro-1,3-dithia-2-stibacyclopentane and the ammonium/sodium salt of the corresponding phosphorus based ligands in an equimolar ratio in anhydrous benzene solution. These yellow crystalline solid/semi-solid derivatives have been characterized by elemental analysis (C, H, S and Sb), molecular weights, melting point as well as spectral [UV, IR and NMR (H-1, C-13 and P-31)] studies. Single crystal X-ray diffraction analyses of 1,3-dithia-2-stibacyclopentane 2,3-butylenedithiophosphate revealed a monodentate mode of bonding of the dithiophosphate ligand in the complex. The free ligands and their antimony(111) complexes have also been screened for their antibacterial and antifungal activities. (C) 2006 Elsevier Ltd. All rights reserved.